Europe — EMA
Olimel N9
GNH USA supplies Olimel N9 (amino acid blend), a nutritional supplement for post‑operative recovery, renal support and malnutrition.
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What is Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin?
Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin, the active ingredient in Olimel N9, is a mixture of essential and non‑essential amino acids presented as a powder for oral use. It supports metabolic functions and protein synthesis in patients requiring nutritional supplementation.
GNH USA supplies Olimel N9 as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals and clinics worldwide.
What is Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin used for?
Olimel N9 provides amino acid supplementation for conditions where protein turnover is increased or intake is insufficient. - Post‑operative recovery: helps maintain nitrogen balance and supports tissue repair. - Chronic kidney disease: assists in managing amino‑acid loss during dialysis. - Malnutrition or cachexia: contributes to improved nutritional status and lean‑body mass. - Severe burns or trauma: supplies essential building blocks for wound healing. - Inborn errors of metabolism: provides specific amino acids required for metabolic control.
What are the side effects of Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin?
Amino‑acid mixtures are generally well tolerated, but adverse reactions can occur.
Common Side Effects: - Nausea: mild to moderate stomach upset. - Vomiting: occasional expulsion of the dose. - Diarrhea: loose stools, especially with rapid infusion. - Abdominal discomfort: cramping or bloating. - Metallic taste: transient alteration of taste perception. - Headache: mild tension‑type headache.
Serious or Rare Side Effects: - Hyperammonemia: elevated blood ammonia levels, requiring monitoring. - Allergic reaction: rash, itching, or urticaria. - Anaphylaxis: rare but severe systemic hypersensitivity. - Metabolic acidosis: disturbance in acid‑base balance. - Electrolyte imbalance: abnormal serum potassium or calcium levels. - Renal function deterioration: worsening kidney parameters in susceptible patients.
What precautions apply to Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin?
When prescribing Olimel N9, clinicians should consider patient‑specific factors and monitor relevant clinical parameters. - Renal impairment: adjust dosing and monitor serum creatinine. - Hepatic dysfunction: watch for signs of hyperammonemia. - Pregnancy and lactation: use only if clearly needed; benefits must outweigh risks. - Concomitant nutrition therapy: coordinate with total parenteral nutrition regimens. - Electrolyte disturbances: check serum electrolytes before and during therapy. - Store at ambient temperature: keep in original container, protect from moisture and direct sunlight.
What does Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin interact with?
Olimel N9 may interact with other agents that affect nitrogen balance or renal handling of metabolites.
Major Interactions (Avoid): - High‑dose nitrogen‑containing supplements: may cause hyperammonemia. - Certain diuretics (e.g., furosemide): increase risk of electrolyte loss.
Moderate Interactions (Monitor Closely): - Antiepileptic drugs (e.g., valproate): may alter amino‑acid metabolism. - Antibiotics such as aminoglycosides: potential additive nephrotoxicity. - Insulin therapy: amino acids can stimulate insulin release, affecting glucose control. - Oral protein supplements: may lead to excess nitrogen intake. - Parenteral nutrition solutions: require compatibility checks.