Europe — EMA
Olimel N9
GNH USA supplies Olimel N9 (Amino Acid Mix), a parenteral nutrition product for critical care and post‑operative support. Request a quote for global supply.
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What is Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin?
Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin, the active ingredient in Olimel N9, is a mixture of essential and non-essential amino acids presented as a sterile powder for intravenous use. It is intended for nutritional support in patients requiring parenteral amino acid supplementation.
GNH USA supplies Olimel N9 as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals and clinics worldwide.
What is Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin used for?
Olimel N9 provides a comprehensive amino acid profile for patients who need parenteral nutritional support. It is commonly used in the following clinical situations: - Post‑operative recovery: Helps to restore nitrogen balance and support tissue repair. - Critical illness or trauma: Supplies essential amino acids to mitigate catabolism. - Long‑term parenteral nutrition: Provides a balanced amino acid mixture for patients unable to receive enteral feeding. - Severe malnutrition: Contributes to rebuilding lean body mass. - Burn patients: Supports high protein turnover required for wound healing.
What are the side effects of Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin?
Adverse reactions to intravenous amino acid solutions are generally infrequent but can occur.
Common Side Effects: - Mild infusion‑related erythema or warmth at the site. - Transient nausea or vomiting. - Slight increase in serum urea nitrogen. - Mild headache. - Low‑grade fever. - Temporary hyperglycaemia.
Serious or Rare Side Effects: - Anaphylactic or severe hypersensitivity reaction. - Acute metabolic acidosis. - Hyperosmolar hyperglycaemic state. - Severe electrolyte disturbances (e.g., hyperkalemia, hypophosphatemia). - Renal impairment exacerbation. - Thrombophlebitis at the infusion site.
What precautions apply to Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin?
When using Olimel N9, clinicians should consider several safety measures: - Renal function: Assess baseline creatinine and adjust infusion rate in renal impairment. - Electrolyte balance: Monitor serum electrolytes regularly during therapy. - Metabolic status: Check acid‑base balance, especially in patients with respiratory or metabolic disorders. - Fluid overload: Evaluate total daily fluid volume to avoid volume excess. - Compatibility: Verify compatibility with other intravenous solutions before mixing. - Store at ambient temperature: keep in original container, protect from moisture and direct sunlight.
What does Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin interact with?
Intravenous amino acid mixtures may interact with certain medications and clinical conditions.
Major Interactions (Avoid): - High‑dose insulin: May potentiate hypoglycaemia when combined with amino acid‑rich solutions. - Certain diuretics (loop, thiazide): Can exacerbate electrolyte shifts. - Acidifying agents: May increase risk of metabolic acidosis.
Moderate Interactions (Monitor Closely): - Anticoagulants: Monitor coagulation parameters as amino acids can affect plasma protein binding. - Corticosteroids: May increase protein catabolism, requiring dose adjustments. - Parenteral lipid emulsions: Observe for compatibility and osmolarity changes.