GNH USA

Europe — EMA

Olimel N5e

GNH USA supplies Olimel N5e (amino acid supplement), a product for parenteral nutrition support and metabolic disorder management. Request a quote for supply.

Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin

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What is Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin?

Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin, the active ingredient in Olimel N5e, is a amino acid supplement presented as an intravenous solution for intravenous use. It supports protein synthesis and metabolic processes in patients requiring parenteral nutrition. It is particularly used in critical care, surgical and oncology settings.

GNH USA supplies Olimel N5e as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, transplant centres, oncology centres and pharmacies worldwide with a focus on quality assurance and regulatory compliance.

What is Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin used for?

Olimel N5e is an intravenous amino acid supplement used to support parenteral nutrition and metabolic balance.

Parenteral nutrition support: Provides essential amino acids to meet protein requirements in patients unable to receive oral intake. Metabolic disorder management: Supplies amino acids for individuals with inborn errors of metabolism requiring specific amino acid supplementation. Post‑operative and trauma recovery: Aids tissue repair and nitrogen balance during the healing phase after surgery, injury or severe burns.

What are the side effects of Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin?

Intravenous administration of Olimel N5e may be associated with the following adverse reactions.

Common Side Effects: - Infusion site irritation: Redness, pain, or phlebitis at the catheter site. - Mild nausea: Transient nausea or vomiting during or shortly after infusion. - Transient hyperglycemia: Slight increase in blood glucose levels, especially in diabetic patients. - Electrolyte imbalance: Minor shifts in serum potassium or calcium concentrations.

Serious or Rare Side Effects: - Anaphylactic reaction: Severe hypersensitivity requiring immediate medical intervention. - Metabolic acidosis: Significant drop in blood pH due to acid accumulation. - Hyperammonemia: Elevated ammonia levels that may lead to neurologic symptoms.

What precautions apply to Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin?

When using Olimel N5e, clinicians should observe the following precautions.

Renal impairment: Adjust dose and monitor renal function tests. Hepatic dysfunction: Observe liver enzymes and ammonia levels. Inborn errors of metabolism: Avoid in patients with specific amino acid disorders such as phenylketonuria. Electrolyte disturbances: Correct serum electrolytes before infusion. Allergic reactions: Monitor for signs of hypersensitivity during administration. Store at 2-8°C: Keep refrigerated, protect from light, do not freeze or shake.

What does Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin interact with?

Potential drug interactions with Olimel N5e should be considered.

Major Interactions (Avoid): - Concurrent high-dose potassium chloride: Risk of hyperkalemia. - Co‑administration with other parenteral nutrition solutions containing overlapping amino acids: Potential amino acid overload.

Moderate Interactions (Monitor Closely): - Diuretics: May exacerbate electrolyte shifts during infusion. - Insulin therapy: Can influence glucose control when hyperglycemia occurs. - Corticosteroids: May increase protein catabolism, affecting amino acid requirements.

Frequently asked questions

What is Olimel N5e used for?+
Olimel N5e is an intravenous amino acid supplement employed in clinical nutrition to provide essential amino acids for patients who cannot receive oral intake. It is commonly used in parenteral nutrition, postoperative care, trauma, burns, and certain metabolic disorders where protein synthesis support is required.
How does the amino acid blend in Olimel N5e work?+
The blend delivers ten essential amino acids directly into the bloodstream, bypassing the gut. These amino acids serve as building blocks for protein synthesis, stimulate the mTOR pathway, replenish nitrogen pools, and support the production of enzymes and neurotransmitters, thereby helping maintain metabolic balance in patients receiving parenteral nutrition.
What is the usual dose of Olimel N5e?+
The prescribed dose of Olimel N5e is individualized by the treating physician based on the patient’s nutritional needs, body weight, renal and hepatic function, and the composition of the overall parenteral regimen. No standard dose is provided here; the prescriber determines the appropriate amount.
Is Olimel N5e safe during pregnancy or breastfeeding?+
Safety data for Olimel N5e in pregnancy or lactation are limited. Because it is a nutritional supplement, it may be used when the potential benefit outweighs any risk, but the decision should be made by the prescribing clinician in consultation with obstetric care. No specific contraindication is listed.
How do I order Olimel N5e from GNH USA?+
Submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain if required) and the necessary import documentation.
How does Olimel N5e compare with other amino acid IV products?+
Olimel N5e offers a balanced blend of ten essential amino acids in a single vial that meets EU quality standards. Compared with formulations containing fewer components, it may provide a more comprehensive amino acid profile, but clinical choice depends on patient-specific needs, compatibility with other nutrients, and institutional protocols.
What are the storage and handling requirements for Olimel N5e?+
Olimel N5e should be stored at 2‑8 °C, protected from light, and must not be frozen or shaken. Before use, inspect the solution for particulate matter or discoloration, and allow it to reach room temperature if required for infusion. Follow aseptic techniques during preparation.
How is Olimel N5e administered?+
The solution is administered intravenously, typically via a peripheral or central venous catheter, as part of a parenteral nutrition regimen. Infusion rates are set by the prescribing clinician and may be adjusted based on the patient’s metabolic tolerance, fluid balance, and concurrent therapies. Compatibility with other IV solutions should be confirmed before mixing.
What are the most serious risks associated with Olimel N5e?+
Serious adverse reactions include anaphylactic or severe hypersensitivity responses, metabolic acidosis, hyperammonemia, and significant electrolyte disturbances. Clinicians should monitor vital signs, laboratory parameters, and the infusion site during and after administration, and be prepared to intervene promptly if severe reactions occur.
Who should not use Olimel N5e?+
Patients with known hypersensitivity to any of the listed amino acids, those with inborn errors of metabolism affecting these amino acids (e.g., phenylketonuria), and individuals with severe renal or hepatic impairment without appropriate dose adjustment should avoid Olimel N5e unless a specialist determines it is safe.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.
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Product details

Drug
Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin
Route
Intravenous Use
Manufacturer
Baxter Medical Ab
Origin
EU