Europe — EMA
Olimel N12e
GNH USA supplies Olimel N12e (amino acids), a nutritional supplement for protein synthesis support in malnutrition and recovery.
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What is Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin?
Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin, the active ingredients in Olimel N12e, are essential amino acids presented as a powder for oral use. They support protein synthesis and nutritional needs in patients requiring amino‑acid supplementation.
GNH USA supplies Olimel N12e as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, transplant centres, oncology centres, pharmacies and clinics worldwide.
What is Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin used for?
Olimel N12e provides essential amino acids that aid metabolic support and tissue repair.
Malnutrition: supports recovery by supplying indispensable amino acids. Post‑surgical recovery: enhances protein synthesis for wound healing. Chronic kidney disease (diet‑managed): provides essential amino acids while limiting nitrogen load. Severe burns: assists in rebuilding damaged tissue and maintaining nitrogen balance.
What are the side effects of Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin?
Common Side Effects: - Nausea: mild upset stomach after ingestion. - Abdominal discomfort: transient cramping or bloating. - Diarrhea: loose stools in some individuals. - Flatulence: increased intestinal gas. - Headache: occasional mild headache. - Taste alteration: temporary change in flavor perception.
Serious or Rare Side Effects: - Allergic reaction: rash, itching, or swelling. - Anaphylaxis: rare but severe hypersensitivity requiring emergency care. - Hyperammonemia: elevated ammonia levels in susceptible patients. - Metabolic imbalance: disturbances in nitrogen metabolism. - Renal overload: potential strain on compromised kidneys. - Severe hypersensitivity: systemic symptoms such as fever or chills.
What precautions apply to Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin?
Before using Olimel N12e, consider the following precautions: - Assess renal function: adjust use in patients with renal impairment. - Monitor liver function: avoid in severe hepatic disease. - Check for phenylketonuria: avoid in PKU patients due to phenylalanine content. - Pregnancy and lactation: use only if clearly needed and prescribed. - Review concomitant medications: evaluate potential interactions. - Store at ambient temperature: keep in original container, protect from moisture and heat.
What does Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin interact with?
Olimel N12e may interact with other agents as follows:
Major Interactions (Avoid): - Concurrent high‑dose nitrogenous waste precursors: risk of hyperammonemia. - Intravenous amino‑acid solutions: incompatibility and precipitation risk.
Moderate Interactions (Monitor Closely): - Diuretics: may increase urinary loss of amino acids. - Insulin therapy: can enhance cellular uptake of amino acids. - Antibiotics affecting gut flora: may alter amino‑acid absorption. - Antiepileptic drugs: possible alteration of plasma amino‑acid levels. - High‑protein diets: may lead to excess nitrogen load.