GNH USA

Europe — EMA

Olimel N12e

GNH USA supplies Olimel N12e (Valine et al.), a amino acid blend for post‑operative, trauma and renal support. Request a quote for global supply.

Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin

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What is Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin?

Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin, the active ingredient in Olimel N12e, is a mixture of essential and non‑essential amino acids presented as a sterile powder for intravenous use. It supports metabolic functions and protein synthesis in patients requiring nutritional supplementation.

GNH USA supplies Olimel N12e as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals and clinics worldwide.

What is Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin used for?

Olimel N12e provides amino acid supplementation for conditions where protein metabolism is compromised. - Post‑operative recovery: helps restore nitrogen balance and supports wound healing. - Severe trauma or burns: contributes to tissue repair and reduces catabolism. - Chronic renal failure on dialysis: supplies essential amino acids that are lost during treatment.

What are the side effects of Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin?

Adverse reactions to amino acid solutions are generally infrequent but may occur.

Common Side Effects: - Mild nausea or vomiting: transient gastrointestinal discomfort after infusion. - Local irritation: redness or pain at the infusion site. - Transient increase in serum urea: temporary rise in nitrogen waste markers. - Mild headache: often related to infusion rate.

Serious or Rare Side Effects: - Hyperammonemia: elevated ammonia levels requiring monitoring. - Allergic reaction: rash, pruritus, or anaphylaxis in susceptible individuals. - Electrolyte imbalance: shifts in potassium or calcium levels. - Metabolic acidosis: rare but serious disturbance of acid‑base balance.

What precautions apply to Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin?

When using Olimel N12e, consider the following safety measures. - Assess renal function: adjust infusion volume in patients with impaired clearance. - Monitor serum electrolytes: watch for potassium or calcium shifts during therapy. - Observe for allergic reactions: discontinue if rash or anaphylaxis develops. - Use aseptic technique: maintain sterility to prevent contamination. - Store at ambient temperature: keep in the original container, protect from moisture and direct sunlight.

What does Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin interact with?

Amino acid solutions can interact with certain medications and clinical conditions.

Major Interactions (Avoid): - High‑dose potassium supplements: may exacerbate hyperkalemia. - Certain anticonvulsants (e.g., phenobarbital): can increase ammonia production.

Moderate Interactions (Monitor Closely): - Diuretics: may alter electrolyte balance when combined with amino acid infusion. - Renal replacement therapies: affect clearance of infused amino acids. - Parenteral nutrition admixtures: require compatibility checks to avoid precipitation.

Frequently asked questions

What is Olimel N12e used for?+
Olimel N12e is an intravenous amino acid formulation used to provide nutritional support in patients who have increased protein‑loss or impaired synthesis, such as after surgery, severe trauma, burns, or during chronic dialysis treatment.
How does the amino acid blend in Olimel N12e work?+
The blend supplies essential and conditionally essential amino acids that are directly taken up by cells and incorporated into new proteins. This replenishes intracellular amino‑acid pools, supports the mTOR pathway, improves nitrogen balance and promotes tissue repair.
What is the usual dose of Olimel N12e?+
The prescribed dose of Olimel N12e is determined by the treating physician based on the patient’s weight, clinical condition, and laboratory parameters. The prescriber sets the infusion volume and rate according to established nutritional guidelines.
Is Olimel N12e safe during pregnancy or breastfeeding?+
Safety data for intravenous amino acid mixtures in pregnancy and lactation are limited. Use is generally reserved for situations where the benefit to the mother outweighs potential risks to the fetus or infant, and only under close medical supervision.
How do I order Olimel N12e from GNH USA?+
To order, submit an enquiry on the product page at gnh-usa.com specifying the required quantity. GNH USA works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any required import documentation.
How does Olimel N12e compare with other amino acid products?+
Olimel N12e contains a broad spectrum of ten amino acids, offering a balanced profile for protein synthesis. Compared with single‑amino‑acid solutions, it provides more comprehensive nutritional support, while its sterile powder form allows flexible reconstitution and dosing.
What are the storage and handling requirements for Olimel N12e?+
Store the powder at ambient temperature, below 25 °C, in the original sealed container. Protect it from moisture, direct sunlight and extreme temperature fluctuations. Reconstitute with the recommended diluent using aseptic technique immediately before administration.
How is Olimel N12e administered?+
Olimel N12e is reconstituted with a suitable sterile diluent and administered intravenously over a controlled period, usually as part of a total parenteral nutrition regimen or as a stand‑alone amino‑acid infusion, following aseptic preparation guidelines.
What are the most serious risks associated with Olimel N12e?+
Serious risks include hyperammonemia, severe allergic reactions such as anaphylaxis, electrolyte disturbances and metabolic acidosis. Patients should be monitored closely for these events, especially during the initial infusion period.
Who should not receive Olimel N12e?+
Patients with known hypersensitivity to any component of the formulation, uncontrolled hyperkalemia, severe hepatic failure with high ammonia levels, or those for whom a balanced amino‑acid supply is contraindicated should not receive Olimel N12e.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.
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Product details

Drug
Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin
Route
Intravenous Use
Manufacturer
Baxter Medical Ab
Origin
EU