GNH USA

Europe — EMA

Olimel N12e

GNH USA supplies Olimel N12e (Essential Amino Acids), a parenteral nutrition supplement for total parenteral nutrition and critical care patients.

Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin

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What is Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin?

Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serine, the active ingredients in Olimel N12e, are a parenteral nutrition supplement presented as a sterile solution for intravenous use. It provides essential amino acids for patients requiring nutritional support, such as those receiving total parenteral nutrition.

GNH USA supplies Olimel N12e as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals and clinics worldwide.

What is Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin used for?

Olimel N12e is used as an intravenous amino acid solution to support protein metabolism in several clinical situations.

- Total parenteral nutrition (TPN): supplies essential amino acids to maintain nitrogen balance when enteral feeding is not possible. - Critical care patients: provides rapid nutritional support during acute illness or trauma. - Post‑operative recovery: aids wound healing and tissue repair when oral intake is limited.

What are the side effects of Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin?

Common Side Effects: - Infusion site erythema or pain: mild local irritation at the catheter site. - Hyperglycemia: transient rise in blood glucose, especially in diabetic patients. - Nausea or vomiting: gastrointestinal discomfort during or after infusion. - Electrolyte shifts: mild changes in potassium or sodium levels. - Fever or chills: reaction to the infusion process. - Headache: transient discomfort during administration.

Serious or Rare Side Effects: - Anaphylactic reaction: severe hypersensitivity requiring immediate medical intervention. - Metabolic acidosis: significant pH imbalance due to rapid amino acid metabolism. - Hepatic dysfunction: elevated liver enzymes in susceptible individuals. - Hyperammonemia: excess ammonia accumulation, particularly in liver disease. - Renal failure: worsening kidney function in patients with pre‑existing renal impairment. - Sepsis related to contamination: infection risk if aseptic technique is breached.

What precautions apply to Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin?

When using Olimel N12e, clinicians should consider several safety measures.

- Assess renal function: adjust infusion volume in patients with impaired kidneys. - Monitor blood glucose: amino acid load may affect glycemic control. - Check for allergies: avoid in individuals with known hypersensitivity to any component. - Use aseptic technique: prevent microbial contamination during preparation and administration. - Limit infusion rate: follow institutional protocols to avoid metabolic complications. - Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

What does Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin interact with?

Olimel N12e may interact with other therapies; awareness of the level of interaction helps guide monitoring.

Major Interactions (Avoid): - Concurrent high‑dose amino acid solutions: risk of hyperammonemia. - Renal replacement therapy: altered clearance may require dose adjustment. - Insulin therapy: potential for severe hypoglycemia if glucose not monitored.

Moderate Interactions (Monitor Closely): - Electrolyte supplements: monitor for potassium or sodium imbalances. - Diuretics: may affect fluid and electrolyte balance during infusion. - Corticosteroids: can increase protein catabolism, influencing amino acid requirements.

Frequently asked questions

What is Olimel N12e used for?+
Olimel N12e is an intravenous amino acid solution used to provide essential nutrients in patients who cannot receive enteral nutrition. It supports protein synthesis, nitrogen balance, and overall metabolic needs during total parenteral nutrition, critical illness, or postoperative recovery.
How does the amino acid blend in Olimel N12e work?+
The blend supplies a balanced mixture of essential and non‑essential amino acids that are directly available for cellular protein synthesis. By bypassing the gastrointestinal tract, the solution quickly restores nitrogen balance, supports immune function, and provides precursors for metabolic pathways.
What is the usual dose of Olimel N12e?+
The prescribed dose of Olimel N12e is determined by the treating physician based on the patient’s weight, clinical condition, and nutritional requirements. Dosage calculations follow institutional protocols for total parenteral nutrition and are individualized for each patient.
Is Olimel N12e safe during pregnancy or breastfeeding?+
Safety data for Olimel N12e in pregnancy and lactation are limited. It should only be used if the potential benefit to the mother outweighs any possible risk to the fetus or infant, and the decision must be made by a qualified healthcare professional.
How do I order Olimel N12e from GNH USA?+
To order, submit an enquiry on the product page at gnh-usa.com with the required quantity. GNH USA works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain if needed), and import documentation.
How does Olimel N12e compare with other parenteral nutrition products?+
Olimel N12e offers a comprehensive essential amino acid profile in a single sterile solution, which can simplify compounding compared with multi‑component TPN regimens. Its formulation is designed for rapid infusion and metabolic stability, whereas some alternatives may require separate amino acid and electrolyte admixtures.
What are the storage and handling requirements for Olimel N12e?+
The product must be stored at 2‑8 °C, protected from light, and kept in its original container. Do not freeze or shake the solution. Before use, inspect for particulate matter or discoloration and follow aseptic techniques during preparation.
How is Olimel N12e administered?+
Olimel N12e is administered intravenously, typically via a central venous catheter or a peripheral line using an infusion pump. The infusion rate is set according to the patient’s metabolic needs and institutional protocols to avoid metabolic complications.
What are the most serious risks associated with Olimel N12e?+
Serious risks include anaphylactic reactions, metabolic acidosis, hyperammonemia, hepatic dysfunction, and renal failure in susceptible patients. Prompt recognition of these events and immediate medical intervention are essential.
Who should not receive Olimel N12e?+
Patients with known hypersensitivity to any of the amino acids, those with uncontrolled metabolic disorders (e.g., severe hepatic failure), or individuals for whom a contraindication to parenteral nutrition exists should not receive Olimel N12e. Clinical judgment is required for each case.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.
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Product details

Drug
Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin
Route
Intravenous Use
Manufacturer
Baxter Sa
Origin
EU