GNH USA

Europe — EMA

Olimel N12e

GNH USA supplies Olimel N12e (Valine, Alanine, Arginine), a nutritional amino‑acid supplement for post‑operative recovery and metabolic support.

Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin

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What is Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin?

Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin, the active ingredient in Olimel N12e, is a mixture of essential and non‑essential amino acids presented as a nutritional supplement for oral use. It supports protein synthesis and metabolic functions in patients requiring specialized nutritional support.

GNH USA supplies Olimel N12e as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals and clinics worldwide.

What is Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin used for?

Olimel N12e provides amino acid supplementation for conditions where protein turnover is increased. - Post‑operative recovery: helps maintain nitrogen balance during tissue healing. - Chronic kidney disease: supports nutritional status when dietary protein is restricted. - Severe burns or trauma: aids in rebuilding lean body mass and wound repair. - Malnutrition in elderly patients: improves overall protein intake and functional status. - Metabolic disorders affecting amino acid utilization: assists in correcting specific deficiencies.

What are the side effects of Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin?

Amino acid supplementation is generally well tolerated, but adverse reactions can occur.

Common Side Effects: - Nausea: mild gastrointestinal discomfort. - Diarrhea: loose stools, usually transient. - Abdominal cramping: intermittent stomach pain. - Metallic taste: temporary alteration of taste perception. - Headache: mild, self‑limiting. - Hyperuricemia: elevated uric acid levels in susceptible individuals.

Serious or Rare Side Effects: - Allergic reaction: rash, itching, swelling, or anaphylaxis. - Metabolic acidosis: rare disturbance of acid‑base balance. - Hyperammonemia: excess ammonia accumulation, particularly in liver disease. - Severe electrolyte imbalance: notable changes in potassium or sodium levels. - Renal impairment worsening: potential decline in kidney function in vulnerable patients. - Hepatotoxicity: rare liver enzyme elevation.

What precautions apply to Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin?

When prescribing Olimel N12e, consider patient‑specific factors and monitor relevant parameters. - Renal function: assess baseline creatinine and adjust use in severe impairment. - Hepatic function: evaluate liver enzymes, especially in patients with cirrhosis. - Metabolic disorders: monitor for hyperammonemia or acid‑base changes. - Pregnancy and lactation: use only if clearly needed, after risk‑benefit assessment. - Drug interactions: review concomitant medications that affect amino acid metabolism. - Store at ambient temperature: keep in original container, protect from moisture and direct sunlight.

What does Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin interact with?

Amino acid mixtures can interact with certain medications and nutrients, requiring attention to avoid reduced efficacy or increased toxicity.

Major Interactions (Avoid): - Levothyroxine: concurrent intake may impair absorption; separate dosing by at least 4 hours. - Anticonvulsants (e.g., phenytoin): may increase hepatic metabolism of amino acids. - High‑dose vitamin C: can enhance renal excretion of certain amino acids.

Moderate Interactions (Monitor Closely): - Diuretics: may exacerbate electrolyte shifts when combined with high amino‑acid loads. - Insulin therapy: amino acids can stimulate insulin release, affecting glucose control. - Oral contraceptives: potential alteration of plasma protein binding.

Frequently asked questions

What is Olimel N12e used for?+
Olimel N12e is an oral nutritional supplement that provides a balanced blend of essential and non‑essential amino acids. It is used to support protein synthesis and metabolic needs in patients with increased catabolic stress, such as after surgery, in chronic kidney disease, severe burns, or other conditions associated with malnutrition.
How does the amino acid blend in Olimel N12e work?+
The formulation supplies the individual amino acids that serve as substrates for protein synthesis and activate the mTOR signaling pathway. By restoring nitrogen balance, it helps promote tissue repair, maintain muscle mass, and support immune function during periods of heightened metabolic demand.
What is the usual dose of Olimel N12e?+
The prescribed dose of Olimel N12e is determined by the treating clinician based on the patient’s nutritional status, underlying condition, and overall treatment plan. Healthcare professionals adjust the amount to meet individual protein and caloric requirements.
Is Olimel N12e safe during pregnancy or breastfeeding?+
Olimel N12e should only be used in pregnancy or lactation when the potential benefit justifies any possible risk. Clinicians should evaluate maternal nutritional needs and monitor both mother and infant closely if the product is prescribed.
How do I order Olimel N12e from GNH USA?+
To request Olimel N12e, submit an enquiry on the product page at gnh-usa.com indicating the required quantity. GNH USA works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.
How does Olimel N12e compare with other amino‑acid supplements?+
Olimel N12e offers a specific combination of ten amino acids, including both essential and conditionally essential ones, formulated for high‑bioavailability. Compared with generic single‑amino‑acid products, it provides a broader substrate profile for protein synthesis, which can be advantageous in complex metabolic states.
What are the storage and handling requirements for Olimel N12e?+
Store Olimel N12e at ambient temperature, below 25 °C, in its original packaging. Protect the product from moisture, excessive heat and direct sunlight to maintain stability and potency.
How is Olimel N12e administered?+
Olimel N12e is taken orally, usually dissolved in water or a suitable beverage as directed by a healthcare professional. The exact administration schedule depends on the patient’s nutritional plan and clinical condition.
What are the most serious risks associated with Olimel N12e?+
Serious adverse reactions, although rare, can include allergic responses such as rash or anaphylaxis, metabolic acidosis, hyperammonemia, significant electrolyte disturbances, worsening renal function, and hepatotoxicity. Prompt medical evaluation is required if any of these occur.
Who should not use Olimel N12e?+
Patients with known hypersensitivity to any of the listed amino acids, those with severe hepatic or renal impairment, or individuals with a history of metabolic disorders that predispose to hyperammonemia should avoid using Olimel N12e unless a clinician determines that benefits outweigh risks.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.
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Product details

Drug
Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin
Route
Intravenous Use
Manufacturer
Baxter Medical Ab
Origin
EU