GNH USA

Europe — EMA

Olimel N12e

GNH USA supplies Olimel N12e (Valine, Alanine, Arginine, etc.), a amino acid solution for parenteral nutrition in patients unable to receive enteral feeding.

Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin

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What is Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin?

Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin, the active ingredient in Olimel N12e, is an amino acid solution presented as a parenteral solution for intravenous use. It provides essential amino acids to support protein synthesis and maintain nitrogen balance in patients who require parenteral nutrition. GNH USA supplies Olimel N12e as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals worldwide.

What is Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin used for?

Olimel N12e, an amino acid solution used in parenteral nutrition, supports protein synthesis and nitrogen balance in patients who cannot receive enteral feeding. - Parenteral nutrition for patients unable to receive enteral feeding: provides essential amino acids to meet nutritional needs. - Critical illness support: helps maintain nitrogen balance and muscle protein synthesis in critically ill patients. - Post‑operative recovery: supplies amino acids to aid tissue repair after major surgery.

What are the side effects of Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin?

Adverse reactions may occur with any intravenous amino acid solution. Monitoring during and after infusion is recommended.

Common Side Effects: - Phlebitis at infusion site - Mild hypernatremia - Transient increase in blood urea nitrogen - Mild metabolic alkalosis

Serious or Rare Side Effects: - Severe hyperammonemia - Anaphylactic or severe allergic reaction - Significant electrolyte disturbances (e.g., hyperkalemia, hyperphosphatemia) - Renal impairment or acute kidney injury

What precautions apply to Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin?

When using Olimel N12e, clinicians should consider several safety measures. - Assess renal function: monitor serum creatinine and urea levels. - Monitor electrolytes: watch for imbalances such as hypernatremia or hyperphosphatemia. - Check for allergy: observe for signs of hypersensitivity during infusion. - Adjust dose in hepatic impairment: consider reduced protein catabolism. - Use aseptic technique: ensure sterile handling during preparation and administration. - Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

What does Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin interact with?

Potential drug interactions should be reviewed before initiating therapy.

Major Interactions (Avoid): - Concurrent high‑dose amino acid solutions: risk of nitrogen overload. - Incompatible IV fluids containing calcium or phosphate: may precipitate. - Renal replacement therapy: can remove administered amino acids, reducing efficacy.

Moderate Interactions (Monitor Closely): - Loop diuretics: may exacerbate electrolyte shifts. - Insulin therapy: amino acids can affect glucose control. - Corticosteroids: increase protein catabolism and may require dose adjustment.

Frequently asked questions

What is Olimel N12e used for?+
Olimel N12e is an intravenous amino acid solution used as part of parenteral nutrition. It supplies essential amino acids to patients who cannot receive nutrition through the gastrointestinal tract, such as those on intensive care, post‑operative recovery, or with severe gastrointestinal dysfunction.
How does the amino acid mixture in Olimel N12e work?+
The mixture provides the building blocks required for protein synthesis. Once infused, the amino acids are taken up by cells, incorporated into new proteins, and help restore nitrogen balance, support tissue repair, and maintain metabolic functions in patients lacking enteral intake.
What is the usual dose of Olimel N12e?+
The dose of Olimel N12e is individualized. A qualified prescriber determines the volume and rate of infusion based on the patient’s weight, clinical condition, renal and hepatic function, and overall nutritional requirements.
Is Olimel N12e safe to use during pregnancy or breastfeeding?+
Safety data for Olimel N12e in pregnancy and lactation are limited. It should only be used when the potential benefit to the mother outweighs any possible risk to the fetus or infant, and under close medical supervision.
How do I order Olimel N12e from GNH USA?+
To order, submit an enquiry on the product page at gnh-usa.com specifying the required quantity. GNH USA works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain where required), and import documentation.
How does Olimel N12e compare with other amino acid solutions?+
Olimel N12e offers a balanced profile of ten essential amino acids in a single formulation, matching the composition of many reference products used in Europe. Compared with some alternatives that contain additional non‑essential amino acids or different ratios, Olimel N12e is designed for straightforward dosing and compatibility with standard parenteral nutrition regimens.
What are the storage and handling requirements for Olimel N12e?+
Olimel N12e must be stored refrigerated at 2‑8 °C. Keep the container in its original packaging, protect it from light, and avoid freezing or shaking. Before use, inspect the solution for particulate matter or discoloration and follow aseptic technique during preparation.
How is Olimel N12e administered?+
The product is administered intravenously as an infusion. It should be added to a compatible carrier solution, mixed under sterile conditions, and infused at a rate prescribed by the treating clinician, typically using an infusion pump to ensure accurate delivery.
What are the most serious risks associated with Olimel N12e?+
Serious risks include severe hyperammonemia, anaphylactic reactions, significant electrolyte disturbances (such as hyperkalemia or hyperphosphatemia), and renal impairment. Patients should be monitored closely for these events, especially during the initial infusion period.
Who should not receive Olimel N12e?+
Olimel N12e is contraindicated in individuals with known hypersensitivity to any of its amino acid components. It should also be used with caution, or avoided, in patients with severe renal failure, uncontrolled electrolyte abnormalities, or those receiving incompatible intravenous solutions.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.
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Product details

Drug
Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin
Route
Intravenous Use
Manufacturer
Baxter Sas
Origin
EU