GNH USA

Europe — EMA

Olimel N12

GNH USA supplies Olimel N12 (Amino Acid Mix), a parenteral nutrition supplement for critical illness, post‑operative recovery and severe malnutrition.

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What is Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin?

Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin, the active ingredient in Olimel N12, is a parenteral nutrition supplement presented as a nutritional formulation for intravenous use. It provides essential amino acids for patients requiring nutritional support, particularly in critical care and postoperative settings.

GNH USA supplies Olimel N12 as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals and transplant centres worldwide.

What is Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin used for?

Olimel N12 is used as a component of parenteral nutrition regimens to support patients with complex metabolic needs. - Critical illness: helps maintain nitrogen balance and supports protein synthesis. - Post‑operative recovery: provides essential amino acids to aid wound healing. - Severe malnutrition: supplies necessary building blocks when oral intake is insufficient. - Long‑term home parenteral nutrition: sustains nutritional status for patients unable to eat orally.

What are the side effects of Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin?

Adverse reactions to Olimel N12 are generally related to its intravenous administration and amino‑acid composition.

Common Side Effects: - Mild fever or chills during infusion. - Transient increase in blood urea nitrogen. - Local irritation at the infusion site. - Mild electrolyte disturbances (e.g., potassium shifts). - Headache. - Nausea.

Serious or Rare Side Effects: - Anaphylactic or severe hypersensitivity reaction. - Metabolic acidosis. - Hyperammonemia. - Severe electrolyte imbalance (e.g., hyperkalemia, hypocalcemia). - Thrombophlebitis at the catheter site. - Renal dysfunction exacerbation.

What precautions apply to Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin?

When prescribing Olimel N12, clinicians should consider patient‑specific factors and monitor relevant parameters. - Renal impairment: adjust infusion rate and monitor nitrogen waste. - Hepatic dysfunction: watch for signs of hyperammonemia. - Electrolyte disorders: check serum electrolytes before and during therapy. - Fluid overload risk: assess volume status, especially in cardiac patients. - Allergic history: verify no known hypersensitivity to amino‑acid solutions. - Store at ambient temperature: keep in original container, protect from moisture and direct sunlight.

What does Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin interact with?

Olimel N12 may interact with other intravenous solutions or medications that affect nitrogen balance and electrolyte status.

Major Interactions (Avoid): - High‑dose potassium chloride admixtures: risk of hyperkalemia. - Acidic drug solutions (e.g., certain antibiotics): may precipitate amino acids.

Moderate Interactions (Monitor Closely): - Loop diuretics: can exacerbate electrolyte shifts. - Corticosteroids: may increase protein catabolism, altering amino‑acid requirements. - Other parenteral nutrition components: ensure compatible mixing ratios. - Anticoagulants: monitor clotting parameters if central line is used.

Frequently asked questions

What is Olimel N12 used for?+
Olimel N12 is an intravenous amino‑acid formulation used as part of parenteral nutrition to provide essential building blocks for protein synthesis in patients who cannot meet their nutritional needs orally, such as those in critical care, after surgery, or with severe malnutrition.
How does the amino‑acid blend in Olimel N12 work?+
The blend delivers a balanced profile of essential and non‑essential amino acids directly into the bloodstream, supporting protein synthesis, nitrogen balance, and metabolic processes like gluconeogenesis, which are vital for recovery and maintenance of lean body mass in nutritionally compromised patients.
What is the usual dose of Olimel N12?+
The prescribed dose of Olimel N12 is individualized by the treating clinician based on the patient’s weight, metabolic needs, and clinical condition. Healthcare professionals calculate the appropriate infusion rate and total daily amount according to established parenteral nutrition guidelines.
Is Olimel N12 safe to use during pregnancy or breastfeeding?+
Safety data for Olimel N12 in pregnancy and lactation are limited. It should only be used when clearly needed and when the potential benefits outweigh any possible risks, under the supervision of a qualified healthcare provider.
How do I order Olimel N12 from GNH USA?+
To order, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain if required) and necessary import documentation.
How does Olimel N12 compare with other parenteral amino‑acid solutions?+
Olimel N12 offers a comprehensive mix of ten essential amino acids, providing a balanced profile that matches many standard amino‑acid formulations. Compared with products that contain additional non‑essential amino acids or specialized ratios, Olimel N12 is suited for general nutritional support where a broad amino‑acid spectrum is required.
What are the storage and handling requirements for Olimel N12?+
Store Olimel N12 at ambient temperature, preferably below 25 °C, in its original packaging. Protect the product from moisture, direct sunlight and extreme temperature fluctuations. Do not freeze; inspect the solution for particulate matter before use.
How is Olimel N12 administered?+
Olimel N12 is administered intravenously, typically diluted in a compatible carrier fluid and infused over a prescribed period using an infusion pump. Administration must follow aseptic technique and be performed by trained healthcare personnel.
What are the most serious risks associated with Olimel N12?+
Serious risks include severe hypersensitivity reactions such as anaphylaxis, metabolic acidosis, hyperammonemia, and significant electrolyte disturbances. Monitoring of vital signs, laboratory parameters and infusion site is essential to detect and manage these events promptly.
Who should not receive Olimel N12?+
Patients with known hypersensitivity to any component of the amino‑acid solution, those with uncontrolled severe electrolyte imbalances, or individuals in whom rapid fluid overload would be hazardous should avoid Olimel N12 unless a risk‑benefit assessment justifies its use.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin
Route
Intravenous Use
Manufacturer
Baxter Medical Ab
Origin
EU