Olimel N12

Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin, the active ingredient in Olimel N12, is a mixture of essential and non‑essential amino acids presented as a sterile powder for intravenous use. It supports metabolic functions and protein synthesis in patients requiring nutritional supplementation.

GNH USA supplies Olimel N12 as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals and clinics worldwide.

Olimel N12 provides amino acid supplementation for conditions where protein turnover is increased or intake is insufficient. - Post‑operative recovery: helps maintain nitrogen balance and supports tissue repair. - Severe burns: contributes to wound healing and reduces catabolism. - Chronic renal failure on dialysis: supplies essential amino acids lost during treatment. - Malnutrition in critical illness: assists in meeting metabolic demands. - Short‑term total parenteral nutrition (TPN): forms part of the amino acid component of TPN regimens.

Adverse reactions to amino acid mixtures are generally infrequent but can occur.

Common Side Effects: - Mild nausea or vomiting - Transient flushing or warmth at the infusion site - Slight increase in serum urea nitrogen - Headache - Mild electrolyte disturbances (e.g., potassium shifts)

Serious or Rare Side Effects: - Severe hypersensitivity or anaphylaxis - Hyperosmolar hyperglycaemic syndrome - Metabolic acidosis - Hyperuricaemia - Renal tubular dysfunction - Thrombophlebitis at the infusion site

When using Olimel N12, consider the following safety measures: - Assess renal function: adjust infusion rate in patients with impaired clearance. - Monitor electrolytes: watch for shifts in potassium, calcium and magnesium. - Evaluate hepatic status: amino acid metabolism may be altered in liver disease. - Observe for signs of infection: maintain aseptic technique during preparation and administration. - Review concomitant nutrition: avoid excessive total nitrogen intake. - Store at ambient temperature: keep in original container, protect from moisture and direct sunlight.

Amino acid solutions can interact with certain medications and clinical conditions.

Major Interactions (Avoid): - High‑dose vitamin C infusions: may increase oxalate load and precipitate renal stones. - Certain anticonvulsants (e.g., phenobarbital): can increase amino‑acid catabolism.

Moderate Interactions (Monitor Closely): - Loop diuretics: may exacerbate electrolyte shifts. - Insulin therapy: amino acids stimulate insulin release, affecting glucose control. - Renal replacement therapies: can remove amino acids, altering intended dosing. - Acid‑base altering agents: may modify the solution’s pH and affect tolerance.