Europe — EMA
Olimel N12
GNH USA supplies Olimel N12 (amino acid mix), a nutritional supplement for post‑operative recovery, malnutrition and metabolic disorders.
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What is Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin?
Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin, the active ingredient in Olimel N12, is a mixture of essential and non‑essential amino acids presented as a powder for oral use. It supports metabolic functions and protein synthesis in patients requiring nutritional supplementation.
GNH USA supplies Olimel N12 as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals and clinics worldwide.
What is Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin used for?
Olimel N12 provides amino acid supplementation for conditions where protein turnover is increased. - Post‑operative recovery: helps maintain nitrogen balance during wound healing. - Chronic kidney disease: supports dietary protein needs when intake is restricted. - Severe malnutrition: contributes to rebuilding lean body mass. - Metabolic disorders: assists in correcting specific amino‑acid deficiencies. - Critical illness (ICU): aids in meeting heightened nutritional requirements.
What are the side effects of Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin?
Amino acid mixtures are generally well tolerated, but adverse reactions can occur.
Common Side Effects: - Nausea: mild gastrointestinal upset reported by some patients. - Abdominal discomfort: bloating or mild cramping. - Diarrhea: loose stools, usually transient. - Headache: occasional mild headache. - Metallic taste: perception of a metallic flavor in the mouth.
Serious or Rare Side Effects: - Allergic reaction: rash, itching, or swelling indicating hypersensitivity. - Hyperammonemia: elevated blood ammonia levels in susceptible individuals. - Metabolic acidosis: rare disturbance of acid‑base balance. - Severe gastrointestinal intolerance: persistent vomiting or severe diarrhea. - Anaphylaxis: life‑threatening systemic reaction requiring immediate medical attention.
What precautions apply to Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin?
Before initiating therapy with Olimel N12, consider the following safety measures. - Renal impairment: adjust dose or monitor nitrogen waste products. - Hepatic dysfunction: watch for signs of hyperammonemia. - Pregnancy & lactation: use only if clearly needed; discuss risks with a physician. - Pediatric use: limit to children under specialist supervision. - Concomitant high‑protein diets: avoid excessive total protein intake. - Store at ambient temperature: keep in original container, protect from moisture and direct sunlight.
What does Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin interact with?
Amino acid formulations can influence the absorption or metabolism of certain medicines.
Major Interactions (Avoid): - Levodopa: may compete for transport across the intestinal wall, reducing efficacy. - Thyroid hormone replacement (levothyroxine): can impair absorption if taken simultaneously.
Moderate Interactions (Monitor Closely): - Anticonvulsants (e.g., valproate): may alter plasma amino‑acid levels. - Antibiotics (tetracyclines, quinolones): chelation risk reducing antibiotic bioavailability. - Iron supplements: decreased iron absorption when co‑administered.