GNH USA

Europe — EMA

Olimel N12

GNH USA supplies Olimel N12 (Amino Acid Blend), a nutrition product for parenteral support in critical illness, surgery and severe malnutrition.

Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin

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What is Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin?

Amino acid blend, the active ingredient in Olimel N12, is a nutrition product presented as a sterile powder for intravenous use. It supports protein synthesis and metabolic needs in patients requiring parenteral nutrition, such as those in critical care or with severe malnutrition.

GNH USA supplies Olimel N12 as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, transplant centres, oncology centres and clinics worldwide.

What is Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin used for?

Olimel N12 provides a balanced amino acid composition for patients requiring parenteral nutrition support.

- Critical illness: helps maintain nitrogen balance and supports tissue repair in intensive care patients. - Post‑operative recovery: supplies essential amino acids to promote wound healing after major surgery. - Severe malnutrition: delivers a complete amino acid profile when oral intake is insufficient. - Chronic kidney disease: provides essential amino acids while limiting nitrogen load for renal‑compromised patients.

What are the side effects of Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin?

Amino acid formulations may be associated with certain adverse reactions.

Common Side Effects: - Nausea or vomiting: mild gastrointestinal discomfort during or after infusion. - Hyperglycemia: transient rise in blood glucose, especially in diabetic patients. - Electrolyte disturbances: mild shifts in potassium, calcium, or magnesium levels. - Infusion site reactions: erythema, warmth, or mild pain at the catheter site.

Serious or Rare Side Effects: - Anaphylaxis: severe allergic reaction requiring immediate medical intervention. - Metabolic acidosis: significant pH imbalance in susceptible individuals. - Hepatic dysfunction: elevated liver enzymes indicating liver stress. - Renal impairment: worsening kidney function in patients with pre‑existing disease. - Severe electrolyte imbalance: dangerous hyper‑ or hypo‑kalemia or calcium disturbances. - Thrombophlebitis: inflammation and clot formation at the infusion site.

What precautions apply to Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin?

When using Olimel N12, consider the following safety measures.

- Renal function: assess kidney status before initiation and monitor during therapy. - Hepatic function: evaluate liver enzymes in patients with liver disease. - Electrolyte balance: correct pre‑existing abnormalities prior to infusion. - Blood glucose: monitor closely in diabetic or hyperglycaemic patients. - Allergy history: verify no known hypersensitivity to any amino acid component. - Store at ambient temperature: keep in original packaging, protect from moisture and direct sunlight.

What does Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin interact with?

Amino acid mixtures can interact with other intravenous solutions and systemic therapies.

Major Interactions (Avoid): - High‑dose glucose solutions: may exacerbate hyperglycaemia when co‑administered. - Potassium‑rich fluids: increase risk of hyperkalaemia. - Calcium‑containing solutions: potential for precipitation and reduced efficacy.

Moderate Interactions (Monitor Closely): - Diuretics: may amplify electrolyte shifts; monitor serum levels. - Insulin therapy: adjust insulin dosage due to glucose load from the formulation. - Renal replacement therapy: may alter amino acid clearance, requiring dose adjustments.

Frequently asked questions

What is Olimel N12 used for?+
Olimel N12 is an intravenous amino acid mixture used to provide essential nutrients for patients who cannot meet their protein and caloric needs through oral intake. It is commonly employed in intensive care, post‑surgical recovery, severe malnutrition, and certain chronic conditions where parenteral nutrition is indicated.
How does the amino acid blend in Olimel N12 work?+
The blend supplies a complete set of essential and non‑essential amino acids that are directly incorporated into the body’s protein synthesis pathways. By restoring nitrogen balance and stimulating anabolic signaling, it supports tissue repair, immune function, and metabolic processes in patients receiving parenteral nutrition.
What is the usual dose of Olimel N12?+
The dosage of Olimel N12 is individualized by the prescribing clinician based on the patient’s weight, clinical condition, renal and hepatic function, and overall nutritional goals. Healthcare professionals calculate the appropriate amount and infusion rate to meet specific nutritional requirements.
Is Olimel N12 safe to use during pregnancy or breastfeeding?+
Safety data for Olimel N12 in pregnancy and lactation are limited. It should only be used if the potential benefit to the mother outweighs any possible risk to the fetus or infant, and the decision must be made by a qualified healthcare provider.
How do I order Olimel N12 from GNH USA?+
To order Olimel N12, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements), and necessary import documentation.
How does Olimel N12 compare with other parenteral nutrition amino acid products?+
Olimel N12 offers a balanced profile of ten essential amino acids designed for broad clinical use. Compared with some single‑component or limited‑spectrum formulations, it provides a more comprehensive amino acid spectrum, which can simplify compounding and reduce the need for additional supplements in many nutritional protocols.
What are the storage and handling requirements for Olimel N12?+
Olimel N12 should be stored at ambient temperature, below 25 °C, in its original sealed container. Protect the product from moisture, direct sunlight, and extreme temperature fluctuations. Do not use if the packaging is damaged or the powder appears clumped or discoloured.
How is Olimel N12 administered?+
Olimel N12 is supplied as a sterile powder for reconstitution with a suitable diluent and is administered intravenously, typically via a central venous catheter. The infusion rate is set by the clinician according to the patient’s nutritional plan and tolerance, and the solution is monitored for compatibility with other IV fluids.
What are the most serious risks associated with Olimel N12?+
Serious risks include anaphylactic reactions, severe electrolyte disturbances, metabolic acidosis, hepatic or renal dysfunction, and thrombophlebitis at the infusion site. Prompt recognition and management of these events are essential, and patients should be monitored closely during and after infusion.
Who should not use Olimel N12?+
Olimel N12 should be avoided in patients with known hypersensitivity to any of its amino acid components, uncontrolled hyperkalemia, severe hepatic failure, or in those where the risk of fluid overload outweighs the nutritional benefit. Clinical judgment is required for patients with unstable metabolic conditions.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.
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Product details

Drug
Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin
Route
Intravenous Use
Manufacturer
Baxter Médico-Farmacêutica, Lda.
Origin
EU