GNH USA

Europe — EMA

Olimel N12

GNH USA supplies Olimel N12 (Amino Acid Mix), a parenteral nutrition supplement for critical care, post‑operative and malnutrition support.

Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin

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What is Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin?

Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin, the active ingredient in Olimel N12, is a parenteral nutrition supplement presented as a intravenous formulation for adult patients requiring nutritional support. It is used to provide essential amino acids in clinical situations where oral intake is insufficient or impossible.

GNH USA supplies Olimel N12 as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals and transplant centres worldwide.

What is Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin used for?

Olimel N12 is a parenteral nutrition supplement that supports patients with metabolic and nutritional needs in several clinical settings. - Critical care: helps maintain nitrogen balance and supports tissue repair in intensive care patients. - Post‑operative recovery: provides essential amino acids to aid wound healing after major surgery. - Severe malnutrition: supplies necessary building blocks when oral nutrition is not feasible. - Chronic kidney disease on dialysis: assists in meeting protein requirements while managing uremic toxicity. - Gastrointestinal failure: delivers nutrients directly into the bloodstream when the gut cannot absorb them.

What are the side effects of Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin?

Adverse reactions may occur with any intravenous amino‑acid solution. Monitoring during infusion is recommended.

Common Side Effects: - Mild fever or chills during infusion. - Transient increase in blood urea nitrogen. - Slight elevation of liver enzymes. - Local irritation at the infusion site. - Mild electrolyte shifts (e.g., potassium, calcium).

Serious or Rare Side Effects: - Anaphylactic or severe hypersensitivity reaction. - Hyperammonemia leading to neurologic symptoms.\n- Metabolic acidosis. - Severe electrolyte imbalance (e.g., hyperkalemia, hypocalcemia). - Thrombophlebitis at the catheter site.

What precautions apply to Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin?

Before initiating therapy, clinicians should assess patient-specific factors and monitor relevant parameters. - Renal function: adjust infusion rate in patients with impaired clearance. - Hepatic function: monitor liver enzymes and ammonia levels. - Electrolytes: check serum electrolytes before and during therapy. - Fluid balance: avoid overload in patients with cardiac failure. - Infusion rate: administer according to manufacturer guidelines to reduce risk of reactions. - Store at 2‑8°C: keep refrigerated, protect from light, do not freeze or shake.

What does Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin interact with?

Amino‑acid solutions can interact with certain drugs and metabolic conditions.

Major Interactions (Avoid): - High‑dose potassium chloride: may cause dangerous hyperkalemia when combined. - Certain anticonvulsants (e.g., valproate): can increase ammonia production.

Moderate Interactions (Monitor Closely): - Loop diuretics: may exacerbate electrolyte shifts. - Insulin therapy: amino acids stimulate insulin release, affecting glucose control. - Acid‑base altering agents: may modify the solution's pH and affect tolerance.

Frequently asked questions

What is Olimel N12 used for?+
Olimel N12 is an intravenous amino‑acid solution used as a parenteral nutrition supplement. It provides essential and non‑essential amino acids to patients who cannot meet their protein needs through oral or enteral feeding, such as those in intensive care, after major surgery, or with severe malnutrition.
How does the amino‑acid blend in Olimel N12 work?+
The blend supplies a balanced profile of essential and non‑essential amino acids that enter the bloodstream directly. Cells take up these amino acids for protein synthesis, supporting tissue repair, immune function, and maintaining plasma oncotic pressure while bypassing the gastrointestinal tract.
What is the usual dose of Olimel N12?+
The dose of Olimel N12 is individualized by the prescribing clinician based on the patient’s weight, metabolic status, renal and hepatic function, and overall nutritional goals. The prescriber determines the infusion rate and total daily amount required for each patient.
Is Olimel N12 safe to use during pregnancy or breastfeeding?+
Safety data for Olimel N12 in pregnancy and lactation are limited. It should only be used when clearly needed and when the potential benefits outweigh any potential risks to the mother or fetus. Clinicians should consult current guidelines and consider alternative nutrition strategies when possible.
How do I order Olimel N12 from GNH USA?+
To order, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain if required) and import documentation.
How does Olimel N12 compare with other parenteral nutrition products?+
Olimel N12 offers a comprehensive amino‑acid profile similar to other commercial amino‑acid solutions but is distinguished by its EU‑origin formulation and compliance with GMP standards. Compared with lipid‑based or mixed‑substrate parenteral formulas, it focuses solely on amino‑acid provision, allowing clinicians to combine it with separate carbohydrate and lipid modules as needed.
What are the storage and handling requirements for Olimel N12?+
Olimel N12 should be stored at 2‑8°C, protected from light, and kept in its original container. Do not freeze or shake the solution. Before use, allow the product to reach room temperature if required by the administration protocol.
How is Olimel N12 administered?+
Olimel N12 is administered intravenously, typically via a central or peripheral venous catheter. The infusion rate is set according to the prescribing clinician’s orders, and the solution is delivered over a controlled period to minimize infusion‑related reactions.
What are the most serious risks associated with Olimel N12?+
Serious risks include severe hypersensitivity reactions such as anaphylaxis, hyperammonemia, metabolic acidosis, and significant electrolyte disturbances. Continuous monitoring during infusion helps detect these events early, allowing prompt intervention.
Who should not receive Olimel N12?+
Patients with known hypersensitivity to any component of the formulation, uncontrolled severe electrolyte imbalances, or those at high risk for hyperammonemia should not receive Olimel N12 unless the benefits clearly outweigh the risks and appropriate monitoring is in place.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.
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Product details

Drug
Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin
Route
Intravenous Use
Manufacturer
Baxter Sa
Origin
EU