GNH USA

Europe — EMA

Olimel N12

GNH USA supplies Olimel N12 (Valine, Alanine, Arginine), a nutritional amino acid powder for malnutrition and post‑operative support.

Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin

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What is Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin?

Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin, the active ingredient in Olimel N12, is a mixture of essential and non‑essential amino acids presented as a powder for oral use. It supports metabolic functions and protein synthesis in patients requiring nutritional supplementation.

GNH USA supplies Olimel N12 as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals and clinics worldwide.

What is Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin used for?

Olimel N12 provides amino acid supplementation that supports several clinical situations where protein intake is compromised. - Malnutrition: Helps restore nitrogen balance and supports tissue repair. - Post‑operative recovery: Contributes to wound healing and muscle preservation. - Chronic kidney disease (conservative management): Supplies essential amino acids while limiting nitrogen load. - Severe burns: Assists in meeting heightened protein requirements for recovery. - Long‑term parenteral nutrition: Provides a balanced amino acid profile for patients unable to use the gastrointestinal tract.

What are the side effects of Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin?

Olimel N12 is generally well tolerated, but adverse reactions may occur.

Common Side Effects: - Nausea: mild to moderate gastrointestinal discomfort. - Abdominal discomfort: bloating or mild cramping. - Diarrhea: loose stools, usually transient. - Metallic taste: temporary alteration in taste perception. - Headache: mild headache without other neurological signs.

Serious or Rare Side Effects: - Allergic reaction: rash, itching, swelling, or anaphylaxis. - Hyperammonemia: elevated blood ammonia levels in susceptible individuals. - Metabolic acidosis: rare disturbance of acid‑base balance. - Severe electrolyte imbalance: uncommon shifts in potassium or sodium levels. - Renal function deterioration: rare worsening of kidney parameters in high‑risk patients.

What precautions apply to Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin?

When using Olimel N12, consider the following safety measures. - Assess renal function: adjust use in patients with impaired kidney clearance. - Monitor liver enzymes: watch for signs of hepatic stress during prolonged therapy. - Evaluate nutritional status: ensure supplementation aligns with overall dietary plan. - Observe for hypersensitivity: discontinue if allergic signs appear. - Store below 25°C: keep in the original container, protect from moisture and direct sunlight.

What does Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin interact with?

Olimel N12 may interact with certain medications and nutrients.

Major Interactions (Avoid): - High‑dose nitrogen‑based drugs: may increase risk of hyperammonemia. - Certain anticonvulsants (e.g., valproate): can alter amino acid metabolism.

Moderate Interactions (Monitor Closely): - Diuretics: may affect electrolyte balance when combined with amino acid load. - Insulin therapy: amino acids can influence glucose homeostasis. - Oral protein supplements: risk of excessive protein intake. - Mineral supplements (e.g., zinc, copper): may compete for absorption. - Antibiotics that affect gut flora: could modify amino acid absorption.

Frequently asked questions

What is Olimel N12 used for?+
Olimel N12 is an oral amino‑acid powder that provides a balanced blend of essential and non‑essential amino acids. It is used to supplement protein intake in patients with malnutrition, after surgery, in chronic kidney disease, severe burns, or when long‑term parenteral nutrition is required.
How does the amino‑acid blend in Olimel N12 work?+
The amino acids are absorbed in the gut and enter the bloodstream, where they act as building blocks for protein synthesis, support nitrogen balance, and serve as precursors for neurotransmitters and metabolic pathways. This helps maintain tissue integrity and supports immune and metabolic functions.
What is the usual dose of Olimel N12?+
The prescribed dose of Olimel N12 is determined by the treating clinician based on the patient’s nutritional status, underlying condition, and overall treatment plan. Healthcare professionals calculate the appropriate amount to meet individual protein and amino‑acid requirements.
Is Olimel N12 safe to use during pregnancy or breastfeeding?+
Safety data for Olimel N12 in pregnancy and lactation are limited. It should only be used if the prescriber judges that the potential benefit outweighs any possible risk to the mother or infant. Consultation with a healthcare professional is essential before use.
How do I order Olimel N12 from GNH USA?+
To order, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any required import documentation.
How does Olimel N12 compare with other amino‑acid supplements?+
Olimel N12 offers a comprehensive profile of ten amino acids, providing both essential and non‑essential components in a single formulation. Compared with single‑amino‑acid products, it delivers a broader spectrum that more closely mimics natural protein composition, which can be advantageous for comprehensive nutritional support.
What are the storage and handling requirements for Olimel N12?+
Store Olimel N12 below 25 °C in its original packaging, protecting it from moisture, heat and direct sunlight. Keep the container tightly closed to maintain stability and prevent contamination.
How is Olimel N12 administered?+
The powder is intended for oral use. It is typically reconstituted in water or a suitable beverage according to the prescriber’s instructions and taken with or without food, depending on the clinical protocol.
What are the most serious risks associated with Olimel N12?+
Serious risks, though rare, include allergic reactions such as rash, itching or anaphylaxis, hyperammonemia, metabolic acidosis, severe electrolyte disturbances and worsening renal function in susceptible patients. Any signs of these reactions require immediate medical attention.
Who should not use Olim: +
Patients with known hypersensitivity to any of the listed amino acids, those with severe renal impairment not managed by a specialist, and individuals with a history of metabolic disorders that affect amino‑acid processing should avoid using Olimel N12 unless a physician determines it is safe.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.
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Product details

Drug
Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin
Route
Intravenous Use
Manufacturer
Baxter Oy
Origin
EU