Europe — EMA
Olimel E
GNH USA supplies Olimel E (amino acids), an amino acid solution for parenteral nutrition in postoperative, trauma and critical patients. Request a quote.
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What is Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin?
A mixture of essential and non‑essential amino acids, the active ingredient in Olimel E, is an amino acid solution presented as a solution for injection for intravenous use. It provides nutrition for patients who cannot receive enteral feeding, such as postoperative, trauma, or critically ill patients.
GNH USA supplies Olimel E as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals worldwide.
What is Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin used for?
Olimel E is used in parenteral nutrition to meet protein and nitrogen requirements in patients unable to tolerate enteral feeding.
- Postoperative patients: supports protein synthesis and nitrogen balance during recovery. - Trauma patients: provides essential amino acids for tissue repair and metabolic needs. - Critically ill patients: maintains nitrogen balance when oral/enteral intake is insufficient. - Severely malnourished patients: supplies amino acids to prevent catabolism. - Major surgery patients: aids postoperative healing and immune function.
What are the side effects of Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin?
Adverse reactions may occur with intravenous amino acid solutions.
Common Side Effects: - Hyperglycemia: elevated blood glucose levels. - Electrolyte disturbances: changes in potassium, sodium, or calcium. - Infusion site reactions: redness, pain, or swelling. - Nausea or vomiting. - Headache. - Fever.
Serious or Rare Side Effects: - Anaphylaxis: severe allergic reaction. - Metabolic acidosis: abnormal blood pH. - Hepatic dysfunction: liver enzyme elevations. - Hyperammonemia: elevated ammonia levels. - Renal impairment: decreased kidney function. - Thrombophlebitis: vein inflammation with clot formation.
What precautions apply to Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin?
When using Olimel E, clinicians should consider several safety measures.
- Renal function assessment: evaluate kidney status before initiation. - Hepatic function monitoring: check liver enzymes regularly. - Electrolyte and glucose monitoring: adjust infusion as needed. - Dose adjustment in liver or kidney disease: tailor therapy to organ function. - Hypersensitivity screening: avoid in patients with known amino acid allergies. - Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.
What does Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin interact with?
Olimel E may interact with other medications or solutions.
Major Interactions (Avoid): - Concurrent high‑dose potassium supplements: risk of hyperkalemia. - Co‑administration with other parenteral nutrition solutions: risk of nutrient overload. - Use with nephrotoxic drugs: increased renal stress. - Combination with insulin therapy: potential hypoglycemia. - Simultaneous diuretic therapy: electrolyte imbalance.
Moderate Interactions (Monitor Closely): - Corticosteroids: may alter protein catabolism. - Beta‑agonists: can affect serum potassium levels. - Anticoagulants: possible impact on clotting parameters. - Additional amino acid products: monitor cumulative amino acid load.