Europe — EMA
Oliclinomel N8-800
GNH USA supplies Oliclinomel N8-800 (amino acids), a parenteral nutrition supplement for patients unable to receive enteral feeding or needing protein
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What is Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin?
Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin, the active ingredient in Oliclinomel N8-800, is a amino acid supplement presented as a parenteral nutrition intravenous solution for intravenous use. It supports protein synthesis and metabolic needs in patients who cannot receive enteral feeding.
GNH USA supplies Oliclinomel N8-800 as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals worldwide.
What is Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin used for?
Oliclinomel N8-800, an amino acid solution used in parenteral nutrition, addresses several clinical situations: - Parenteral nutrition (enteral feeding intolerance): Provides essential amino acids for patients who cannot receive enteral nutrition. - Post‑operative care (surgical recovery): Supports protein synthesis and nitrogen balance after major surgery. - Critical illness (intensive care): Supplies amino acids to critically ill patients to maintain metabolic function.
What are the side effects of Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin?
Adverse reactions may occur with intravenous amino acid solutions.
Common Side Effects: - Electrolyte imbalance: mild shifts in sodium, potassium or calcium levels. - Hyperglycemia: transient rise in blood glucose during infusion. - Mild nausea or vomiting: occasional gastrointestinal discomfort. - Local infusion site irritation: redness or discomfort at the catheter site.
Serious or Rare Side Effects: - Anaphylactic reaction: severe allergic response requiring immediate intervention. - Severe metabolic acidosis: significant pH changes in blood. - Renal dysfunction: impaired kidney function in susceptible patients. - Thrombophlebitis: inflammation and clot formation in the vein.
What precautions apply to Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin?
When using Oliclinomel N8-800, consider the following precautions: - Renal impairment: monitor renal function and adjust infusion rate. - Liver disease: use with caution due to altered amino acid metabolism. - Electrolyte disorders: correct existing imbalances before administration. - Hyperammonemia: avoid in patients with urea cycle defects. - Pregnancy: limited data; weigh benefits against potential risks. - Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.
What does Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin interact with?
Potential drug interactions should be reviewed before initiating therapy.
Major Interactions (Avoid): - Concurrent high‑dose amino acid solutions: risk of nitrogen overload. - Incompatible IV solutions containing calcium or phosphate: precipitation risk.
Moderate Interactions (Monitor Closely): - Insulin therapy: may require dose adjustment due to glucose changes. - Diuretics: monitor electrolyte balance closely. - Renal replacement therapy: may affect amino acid clearance and require dosing review.