GNH USA

Europe — EMA

Oliclinomel N7-1000e

GNH USA supplies Oliclinomel N7-1000e (amino acid solution), a parenteral nutrition product for patients unable to receive enteral feeding. Request a quote.

Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin

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What is Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin?

Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin, the active ingredient in Oliclinomel N7-1000e, is an amino acid solution presented as a sterile solution for injection for intravenous use. It provides essential amino acids for patients requiring parenteral nutrition when enteral feeding is not possible.

GNH USA supplies Oliclinomel N7-1000e as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals worldwide.

What is Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin used for?

Oliclinomel N7-1000e is used in parenteral nutrition to address protein and nitrogen needs in several clinical situations. - Inability to tolerate enteral feeding: provides complete amino acid profile to sustain nutrition. - Critical illness or catabolism: supports protein synthesis and reduces muscle loss. - Surgical or trauma recovery: supplements essential amino acids to aid wound healing and recovery. - Metabolic disorders with increased nitrogen loss: helps maintain nitrogen balance.

What are the side effects of Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin?

Amino acid solutions for parenteral nutrition may be associated with several adverse reactions.

Common Side Effects: - Infusion site erythema or pain: mild local irritation at the catheter site. - Transient hyperglycemia: elevation of blood glucose during infusion. - Electrolyte shifts: mild changes in potassium or calcium levels. - Nausea or vomiting: occasional gastrointestinal discomfort.

Serious or Rare Side Effects: - Anaphylactic reaction: severe hypersensitivity requiring immediate medical intervention. - Metabolic acidosis: significant pH disturbance due to amino acid metabolism. - Hyperammonemia: elevated ammonia levels in patients with hepatic impairment. - Severe hypernatremia: high serum sodium from solution composition.

What precautions apply to Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin?

When prescribing Oliclinomel N7-1000e, clinicians should observe the following precautions. - Renal impairment: adjust infusion rate and monitor serum creatinine. - Hepatic dysfunction: avoid in severe liver disease due to risk of hyperammonemia. - Electrolyte monitoring: check serum electrolytes before and during therapy. - Fluid balance: consider total fluid volume to prevent overload. - Known hypersensitivity: discontinue if allergic reaction occurs. - Pregnancy and lactation: use only if benefits outweigh potential risks (category unknown). - Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

What does Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin interact with?

Amino acid solutions can interact with other medications; relevant interactions include:

Major Interactions (Avoid): - Concurrent high‑protein enteral nutrition: may cause nitrogen overload and metabolic imbalance. - Valproic acid therapy: increased risk of hyperammonemia. - Loop diuretics: can exacerbate electrolyte disturbances.

Moderate Interactions (Monitor Closely): - Insulin therapy: may require glucose monitoring due to hyperglycemia risk. - Corticosteroids: can increase protein catabolism, altering amino acid requirements. - Renal replacement therapy: may affect amino acid clearance.

Frequently asked questions

What is Oliclinomel N7-1000e used for?+
Oliclinomel N7-1000e is an intravenous amino acid solution used in parenteral nutrition to provide essential amino acids to patients who cannot receive enteral feeding, such as those in critical care, postoperative recovery, or with severe catabolic states.
How does the amino acid mixture work?+
The mixture supplies a balanced profile of essential and non‑essential amino acids directly into the bloodstream. These amino acids serve as building blocks for protein synthesis, support nitrogen balance, and aid hepatic metabolism, thereby helping maintain tissue integrity and promote healing when oral intake is insufficient.
What is the usual dose?+
The dosage of Oliclinomel N7-1000e is individualized by the prescribing clinician based on the patient’s weight, metabolic needs, and clinical condition. The healthcare professional determines the infusion rate and total daily amount to achieve the desired nitrogen and protein targets.
Is it safe in pregnancy or breastfeeding?+
Safety data for Oliclinomel N7-1000e in pregnancy and lactation are limited, and the product carries an unknown pregnancy category. It should only be used when the potential benefit to the mother outweighs any possible risk to the fetus or infant, and under close medical supervision.
How do I order Oliclinomel N7-1000e from GNH USA?+
To place an order, submit an enquiry on the product page at gnh-usa.com specifying the required quantity. GNH USA works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain if needed), and necessary import documentation.
How does it compare with other parenteral amino acid products?+
Oliclinomel N7-1000e offers a comprehensive blend of ten essential amino acids in a single sterile solution, comparable to other amino acid formulations used for total parenteral nutrition. Differences may lie in the specific amino‑acid ratios, osmolarity, and compatibility with other TPN components, which clinicians consider when selecting a product for individual patient needs.
What are the storage and handling requirements?+
The solution must be stored refrigerated at 2–8 °C, protected from light, and must not be frozen or shaken. Before use, inspect the container for particulate matter or discoloration, and allow the product to reach room temperature if required for infusion, following aseptic technique.
How is the product administered?+
Oliclinomel N7-1000e is administered intravenously, typically via a central venous catheter or a peripheral line, as part of a total parenteral nutrition regimen. The infusion rate is set by the healthcare provider and delivered using an infusion pump to ensure accurate dosing and to monitor for any adverse reactions.
What are the most serious risks to watch for?+
The most serious risks include anaphylactic or severe hypersensitivity reactions, metabolic acidosis, hyperammonemia (especially in patients with liver dysfunction), and significant electrolyte disturbances. Prompt recognition of symptoms such as rash, difficulty breathing, rapid heart rate, or sudden changes in laboratory values is essential for immediate intervention.
Who should not use Oliclinomel N7-1000e?+
Patients with known hypersensitivity to any component of the solution, severe hepatic impairment, uncontrolled electrolyte imbalances, or those for whom intravenous nutrition is contraindicated should not receive Oliclinomel N7-1000e. Clinical judgment is required to assess suitability on an individual basis.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.
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Product details

Drug
Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin
Route
Intravenous Use
Manufacturer
Baxter Sa
Origin
EU