GNH USA

Europe — EMA

Oliclinomel N 4-550e

Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin, the active ingredient in Oliclinomel N 4-550e, is a mixture of essential and non‑essential amino acids presented as a…

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What is Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin?

Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin, the active ingredient in Oliclinomel N 4-550e, is a mixture of essential and non‑essential amino acids presented as a sterile powder for intravenous use. It is intended for clinical situations that require amino acid supplementation, such as metabolic support during intensive care or peri‑operative care.

GNH USA supplies Oliclinomel N 4-550e as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals and transplant centres worldwide.

What is Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin used for?

Oliclinomel N 4-550e provides a broad spectrum amino‑acid formulation that supports patients with metabolic and nutritional needs in several clinical contexts: - Critical care: helps to maintain nitrogen balance and supports protein synthesis during intensive‑care treatment. - Peri‑operative care: contributes to tissue repair and wound healing during the surgical period. - Metabolic disorders: supplies essential amino acids for patients with inborn errors of metabolism or catabolic states. - Long‑term parenteral nutrition: serves as a component of total parenteral nutrition regimens for patients unable to receive enteral feeding.

What are the side effects of Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin?

Amino‑acid solutions administered intravenously can be associated with a range of reactions, most of which are mild and transient.

Common Side Effects: - Phlebitis at the infusion site: mild inflammation of the vein. - Transient hyperglycaemia: temporary rise in blood glucose levels. - Mild electrolyte imbalance: slight changes in serum potassium or calcium. - Nausea or mild gastrointestinal discomfort. - Low‑grade fever: mild increase in body temperature.

Serious or Rare Side Effects: - Anaphylactic reaction: severe allergy requiring immediate medical intervention. - Metabolic acidosis: significant shift in acid‑base balance. - Hyperosmolarity‑related complications: circulatory overload or renal strain. - Severe electrolyte disturbances: marked hyper‑ or hypokalemia. - Sepsis related to catheter contamination. - Acute liver dysfunction in susceptible patients.

What precautions apply to Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin?

When using Oliclinomel N 4-550e, clinicians should observe several safety measures: - Renal function monitoring: assess creatinine and urine output regularly. - Hepatic function monitoring: check liver enzymes and bilirubin levels. - Blood glucose monitoring: watch for hyperglycaemia, especially in diabetic patients. - Electrolyte surveillance: maintain serum potassium, calcium and magnesium within target ranges. - Infusion rate control: administer according to recommended flow rates to avoid osmotic stress. - Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

What does Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin interact with?

Oliclinomel N 4‑550e may interact with other intravenous solutions and medications administered through the same line.

Major Interactions (Avoid): -    ​  Electrolyte‑    ​  ​  ​  ​  ​  ​  ​  ​  ​  ​  ​  ​  ​  ​  ​  ​  ​  ​  ​ ​  ​  ​  ​  ​ -  L  ​  ​  ​  ​  ​  ​  ​  ​  ​  ​  ​  ​  ​  ​  ​  ​  ​  ​  ​  ​  ​  ​  ​  ​  ​  ​  ​  ​ -  C ​ -  D -  E

Moderate Interactions (Monitor Closely): -    ​  ​  C ​  ​  ​  ​ -     -    d  t  t t

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Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin
Route
Intravenous Use
Manufacturer
Baxter Czech Spol. S R.O.
Origin
EU