Olicard Retard (Isosorbide Mononitrate)

Isosorbide Mononitrate, the active ingredient in Olicard Retard, is a vasodilator presented as a sustained‑release oral tablet for once‑daily use in adults with chronic heart‑related chest pain. It helps to prevent angina attacks by improving blood flow to the heart muscle.

GNH USA supplies Olicard Retard as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Olicard Retard contains isosorbide mononitrate, a nitrate that acts on the coronary circulation to relieve angina. - Chronic stable angina: reduces the frequency and severity of chest pain episodes. - Exercise‑induced angina: helps maintain functional capacity during physical activity. - Prevention of angina attacks: provides long‑term prophylaxis against recurrent episodes.

Adverse reactions may occur with any nitrate therapy.

Common Side Effects: - Headache: mild to moderate, often transient. - Flushing: warm sensation with skin reddening. - Dizziness or light‑headedness, especially on standing. - Nausea or abdominal discomfort. - Palpitations or tachycardia.

Serious or Rare Side Effects: - Severe hypotension: marked drop in blood pressure causing fainting. - Methemoglobinemia: abnormal hemoglobin affecting oxygen delivery. - Allergic reactions: rash, itching, swelling, or anaphylaxis. - Syncope: sudden loss of consciousness. - Chest pain worsening: paradoxical increase in angina.

When using Olicard Retard, consider the following safety measures: - Assess cardiovascular status: evaluate blood pressure and heart rate before initiation. - Avoid abrupt discontinuation: taper the dose to prevent rebound angina. - Monitor for drug‑specific side effects: watch for severe headache or hypotension. - Caution in hepatic or renal impairment: dose may need adjustment. - Contraindicated in patients with known hypersensitivity to nitrates. - Store at ambient temperature: keep in the original container, protect from moisture and direct sunlight.

Isosorbide mononitrate may interact with several medicines; monitoring is advised.

Major Interactions (Avoid): - Phosphodiesterase‑5 inhibitors (e.g., sildenafil): risk of profound hypotension. - Other nitrates or nitroglycerin: additive vasodilatory effect leading to severe hypotension. - Guanylate cyclase stimulators: excessive vasodilation.

Moderate Interactions (Monitor Closely): - Antihypertensives (ACE inhibitors, ARBs, beta‑blockers): may enhance blood‑pressure‑lowering effect. - Diuretics: can increase risk of orthostatic hypotension. - Alcohol: may intensify dizziness and hypotensive episodes.