Olfen Patch (Diclofenac Sodium)

Diclofenac Sodium, the active ingredient in Olfen Patch, is a nonsteroidal anti‑inflammatory drug (NSAID) presented as a topical patch for cutaneous use. It reduces pain and inflammation in musculoskeletal conditions and is applied to the skin of adults.

GNH USA supplies Olfen Patch as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Diclofenac Sodium is an NSAID that works locally to relieve pain and inflammation in musculoskeletal and joint conditions.

- Localized musculoskeletal pain: provides targeted analgesia and reduces inflammation at the application site. - Osteoarthritis of the knee: alleviates joint pain and improves function when applied over the affected knee. - Post‑operative incision pain: diminishes discomfort and swelling after minor surgical procedures.

Adverse reactions may occur with topical diclofenac use. Most are mild and limited to the skin, but rare systemic events have been reported.

Common Side Effects: - Skin irritation: redness or discomfort at the application site. - Pruritus: itching of the treated area. - Burning sensation: transient warmth or stinging on the skin.

Serious or Rare Side Effects: - Allergic dermatitis: severe rash, swelling, or blistering. - Stevens‑Johnson syndrome or toxic epidermal necrolysis: life‑threatening skin reactions. - Systemic NSAID toxicity: gastrointestinal ulceration, renal impairment, or cardiovascular events in susceptible individuals.

Before using Olfen Patch, consider the following safety measures.

- Assess skin integrity: ensure the area is clean, intact, and free of lesions before application. - Avoid use on broken or infected skin: damaged skin may increase systemic absorption and irritation. - Limit duration: follow prescriber instructions and do not exceed the recommended wear time. - Monitor for systemic NSAID effects: watch for gastrointestinal, renal, or cardiovascular symptoms. - Avoid concurrent topical NSAIDs: using more than one NSAID patch can increase local irritation. - Store at room temperature: keep in the original packaging, protect from moisture and direct sunlight.

Diclofenac Sodium can interact with other medicines, affecting safety or efficacy.

Major Interactions (Avoid): - Anticoagulants (e.g., warfarin): increased risk of bleeding. - Other NSAIDs or COX‑2 inhibitors: additive gastrointestinal and renal toxicity. - Lithium: diclofenac may raise lithium serum levels, risking toxicity.

Moderate Interactions (Monitor Closely): - ACE inhibitors or diuretics: may reduce renal function, especially in dehydrated patients. - Methotrexate: diclofenac can raise methotrexate concentrations, requiring dose adjustment.