Olfen (Diclofenac Sodium)

Diclofenac Sodium, the active ingredient in Olfen, is a nonsteroidal anti-inflammatory drug (NSAID) presented as an oral dosage form for oral use. It provides analgesic and anti‑inflammatory effects for mild to moderate pain, osteoarthritis, rheumatoid arthritis and other musculoskeletal conditions in adults. GNH USA supplies Olfen as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Olfen, a diclofenac‑based NSAID, acts on inflammatory pathways to relieve pain and swelling. - Mild to moderate pain: provides analgesic relief for acute or chronic pain conditions. - Osteoarthritis: reduces joint pain and improves functional mobility. - Rheumatoid arthritis: diminishes inflammatory joint damage and associated discomfort. - Musculoskeletal pain: alleviates strain‑related soreness and inflammation in muscles and tendons.

Olfen may cause a range of adverse reactions, from mild to serious.

Common Side Effects: - Gastrointestinal upset: nausea, dyspepsia, or abdominal discomfort. - Headache: mild to moderate intensity. - Dizziness or vertigo. - Skin rash or mild itching. - Elevated liver enzymes (asymptomatic).

Serious or Rare Side Effects: - Gastrointestinal ulceration or bleeding. - Hepatic injury with jaundice. - Acute renal impairment or failure. - Cardiovascular events such as myocardial infarction or stroke. - Severe skin reactions (e.g., Stevens‑Johnson syndrome). - Anaphylactic or anaphylactoid reactions.

Before using Olfen, consider the following safety measures. - Assess gastrointestinal risk: avoid in patients with a history of ulcers or bleeding. - Monitor renal function: use caution in those with existing kidney disease. - Avoid in known hypersensitivity to diclofenac or other NSAIDs. - Use the lowest effective dose for the shortest duration needed. - Caution in patients with cardiovascular disease or hypertension. - Store at room temperature: keep in the original packaging, protect from moisture and direct sunlight.

Olfen can interact with several medicines, requiring careful management.

Major Interactions (Avoid): - Anticoagulants (e.g., warfarin): increased bleeding risk. - Other NSAIDs or aspirin: additive gastrointestinal toxicity. - Corticosteroids: heightened ulcer risk. - Lithium: elevated serum lithium levels. - Methotrexate: reduced clearance leading to toxicity.

Moderate Interactions (Monitor Closely): - ACE inhibitors or ARBs: possible reduction in renal function. - Diuretics: risk of renal impairment. - SSRIs or SNRIs: increased bleeding tendency. - Antihypertensives: potential attenuation of blood pressure control. - Oral hypoglycemics: may affect glucose regulation.