Olfen (Diclofenac Sodium)

Diclofenac sodium, the active ingredient in Olfen, is a non‑steroidal anti‑inflammatory drug presented as a 50 mg tablet for oral use. It is indicated for the relief of pain and inflammation associated with musculoskeletal disorders, osteoarthritis and rheumatoid arthritis in adults.

GNH USA supplies Olfen as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Olfen is a non‑steroidal anti‑inflammatory drug that reduces inflammation and pain in several musculoskeletal conditions.

- Osteoarthritis: alleviates joint pain and improves mobility. - Rheumatoid arthritis: decreases joint swelling and stiffness. - Ankylosing spondylitis: reduces spinal pain and inflammation. - Acute musculoskeletal sprain or strain: provides short‑term pain relief. - Post‑operative pain: helps control pain after minor surgical procedures.

Adverse reactions to diclofenac may vary from mild to severe and should be monitored during therapy.

Common Side Effects: - Gastrointestinal discomfort such as nausea, dyspepsia or abdominal pain. - Headache or dizziness. - Skin rash or mild itching. - Elevated liver enzymes. - Fluid retention causing mild peripheral edema.

Serious or Rare Side Effects: - Peptic ulcer disease or gastrointestinal bleeding. - Severe liver injury or hepatitis. - Renal impairment or acute kidney injury. - Cardiovascular events such as myocardial infarction or stroke. - Severe skin reactions including Stevens‑Johnson syndrome. - Anaphylactic shock or severe hypersensitivity.

When prescribing Olfen, clinicians should consider several safety aspects to minimise risk.

- Assess renal function: evaluate baseline renal parameters before treatment. - Monitor hepatic enzymes: periodic liver function tests are advised. - Evaluate cardiovascular risk: use cautiously in patients with existing heart disease. - Avoid concurrent NSAIDs: increased risk of gastrointestinal complications. - Use the lowest effective dose for the shortest duration. - Store at below 25°C: keep in the original packaging, protect from moisture and light.

Diclofenac may interact with several medicines, altering efficacy or safety.

Major Interactions (Avoid): - Anticoagulants (e.g., warfar‑ waf ). -  S         ....

Moderate