Olfen (Diclofenac Sodium)

Diclofenac sodium, the active ingredient in Olfen, is a nonsteroidal anti‑inflammatory drug (NSAID) presented as a topical formulation for local use as part of targeted therapy. It reduces pain and inflammation in musculoskeletal conditions and is intended for adult patients requiring targeted relief.

GNH USA supplies Olfen as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide through regulated channels and quality‑assured logistics. Our global network ensures timely delivery and compliance with local regulatory requirements while maintaining product integrity throughout the supply chain.

Diclofenac sodium is applied topically to manage pain and inflammation in musculoskeletal disorders.

Osteoarthritis: reduces joint pain and improves function in affected joints. Rheumatoid arthritis: alleviates inflammatory pain in peripheral joints. Acute musculoskeletal injury: provides localized relief from sprains, strains and bruises.

Topical diclofenac may cause local and systemic adverse reactions, most of which are mild and reversible.

Common Side Effects: - Skin irritation: redness, itching or burning at the application site. - Dryness: mild peeling or flaking of the skin. - Pruritus: localized itching. - Mild headache: occasional transient headache.

Serious or Rare Side Effects: - Severe allergic reaction: angioedema, swelling of face or throat, requiring immediate medical attention. - Contact dermatitis: severe rash with blistering. - Systemic toxicity: rare hepatic or renal impairment with extensive use.

When using Olfen, consider the following precautions to ensure safe and effective therapy.

Avoid use on broken or infected skin: apply only to intact skin. Limit duration: do not exceed the period recommended by the prescriber, typically up to 7 days per site. Concurrent NSAID use: discuss with healthcare professional to avoid additive toxicity. Pregnancy and lactation: consult a physician before use, as safety data are limited. Children: not recommended for patients under 12 years unless advised by a clinician. Store below 25°C: keep in the original packaging, protect from moisture and direct sunlight.

Diclofenac sodium can interact with other medicines, altering efficacy or increasing risk of adverse effects.

Major Interactions (Avoid): - Anticoagulants (e.g., warfarin): increased risk of bleeding. - Selective COX‑2 inhibitors: additive gastrointestinal toxicity. - Systemic corticosteroids: heightened risk of ulceration.

Moderate Interactions (Monitor Closely): - ACE inhibitors or diuretics: may reduce renal function, monitor kidney parameters. - Lithium: diclofenac can raise lithium levels, require serum monitoring. - Methotrexate: possible increased toxicity, monitor hepatic function.