Olfen 100 Sr (Diclofenac Sodium)

Diclofenac sodium, the active ingredient in Olfen 100 Sr, is a nonsteroidal anti-inflammatory drug (NSAID) presented as a 100 mg tablet for oral use. It treats mild to moderate pain and inflammatory conditions such as osteoarthritis and rheumatoid arthritis in adults.

GNH USA supplies Olfen 100 Sr as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Olfen 100 Sr, a diclofenac sodium NSAID, is employed for conditions involving inflammation and pain.

- Osteoarthritis: reduces joint pain and swelling, improving mobility. - Rheumatoid arthritis: alleviates inflammation and joint stiffness. - Acute musculoskeletal pain: provides analgesia and diminishes inflammation. - Dysmenorrhea: relieves menstrual cramps and associated discomfort. - Post‑operative pain: helps control pain after surgical procedures.

Common Side Effects: - Gastrointestinal upset: nausea, dyspepsia, or abdominal discomfort. - Headache: mild to moderate intensity. - Dizziness: transient sensation of light‑headedness.

Serious or Rare Side Effects: - Gastrointestinal bleeding or ulcer perforation. - Hepatic injury: elevated liver enzymes or jaundice. - Renal impairment: reduced kidney function or acute failure. - Severe skin reactions: Stevens‑Johnson syndrome or toxic epidermal necrolysis. - Cardiovascular events: increased risk of thrombotic episodes.

Olfen 100 Sr should be used with caution in specific clinical situations.

- Assess renal function: monitor creatinine in patients with kidney disease. - Evaluate hepatic status: avoid in severe liver impairment. - Consider cardiovascular risk: use cautiously in patients with a history of heart disease. - Avoid in third‑trimester pregnancy: contraindicated due to fetal risk. - Use with caution with anticoagulants: increased bleeding potential. - Store at ambient temperature: keep below 25°C, protect from moisture and keep in the original packaging.

Olfen 100 Sr may interact with several medicines; monitoring is advised.

Major Interactions (Avoid): - Anticoagulants (warfarin): increased bleeding risk. - Lithium: elevated serum lithium concentrations. - Methotrexate: reduced clearance leading to toxicity.

Moderate Interactions (Monitor Closely): - Diuretics: possible decline in renal function. - Corticosteroids: heightened risk of gastrointestinal ulceration.