Europe — EMA
Olanzapine Sandoz
GNH USA supplies Olanzapine Sandoz (Olanzapine), an atypical antipsychotic for schizophrenia and bipolar I disorder. Request a quote for global supply.
Request sourcing
What is Olanzapine?
Olanzapine, the active ingredient in Olanzapine Sandoz, is an atypical antipsychotic presented as an oral tablet for oral use. It is prescribed for the management of schizophrenia and bipolar I disorder in adult patients.
GNH USA supplies Olanzapine Sandoz as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.
What is Olanzapine used for?
Olanzapine is an atypical antipsychotic used in the treatment of major psychiatric disorders. - Schizophrenia: reduces psychotic symptoms such as delusions, hallucinations and thought disorder. - Bipolar I disorder (manic episodes): controls acute manic symptoms and stabilises mood. - Maintenance therapy: helps prevent relapse of schizophrenia or bipolar disorder when used long‑term.
What are the side effects of Olanzapine?
Olanzapine may cause a range of adverse reactions, from mild to serious.
Common Side Effects: - Weight gain: increased body mass and appetite. - Sedation: drowsiness or reduced alertness. - Dry mouth: reduced salivation. - Constipation: slowed gastrointestinal motility.
Serious or Rare Side Effects: - Neuroleptic malignant syndrome: life‑threatening reaction with fever and muscle rigidity. - Agranulocytosis: severe reduction in white blood cells, increasing infection risk.
What precautions apply to Olanzapine?
When prescribing Olanzapine, clinicians should consider several safety measures. - Metabolic monitoring: regularly assess weight, glucose and lipid levels. - Cardiovascular assessment: evaluate for orthostatic hypotension and QT prolongation. - Seizure risk: use cautiously in patients with a history of seizures. - Elderly patients: avoid in dementia‑related psychosis due to increased mortality risk. - Store at ambient temperature: keep in the original container, protect from moisture and direct sunlight.
What does Olanzapine interact with?
Olanzapine can interact with other medicines, altering its efficacy or safety.
Major Interactions (Avoid): - CYP1A2 inhibitors (e.g., fluvoxamine): may increase olanzapine plasma levels. - CNS depressants (e.g., benzodiazepines): additive sedation and respiratory depression. - Anticholinergic agents: heightened anticholinergic burden.
Moderate Interactions (Monitor Closely): - CYP2D6 inhibitors (e.g., paroxetine): may modestly raise olanzapine concentrations. - Antihypertensives: potential for enhanced hypotensive effect.
