Okitask (Ketoprofen Lysine)

Ketoprofen lysine, the active ingredient in Okitask, is a non‑steroidal anti‑inflammatory drug presented as a tablet for oral use. It is employed to relieve pain and inflammation associated with musculoskeletal disorders, rheumatoid arthritis and other inflammatory conditions in adults.

GNH USA supplies Okitask as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Ketoprofen lysine is an NSAID that reduces inflammation and pain in several musculoskeletal and inflammatory conditions. - Rheumatoid arthritis: helps reduce joint pain, swelling and stiffness. - Osteoarthritis: alleviates pain and improves joint function. - Acute musculoskeletal injury: provides short‑term relief of pain and inflammation. - Post‑operative pain: used as part of multimodal analgesia after surgery. - Dysmenorrhea: reduces menstrual‑related pelvic pain.

Ketoprofen lysine may cause a range of adverse reactions, most of which are dose‑dependent and reversible.

Common Side Effects: - Gastrointestinal discomfort: nausea, dyspepsia or abdominal pain. - Headache: mild to moderate intensity. - Dizziness or light‑headedness. - Skin rash or mild itching. - Elevated liver enzymes.

Serious or Rare Side Effects: - Peptic ulcer disease or gastrointestinal bleeding. - Severe skin reactions such as Stevens‑Johnson syndrome. - Renal impairment or acute kidney injury. - Hepatotoxicity with marked liver enzyme elevation. - Anaphylactic or severe allergic reactions.

When prescribing ketoprofen lysine, clinicians should evaluate patient history and monitor for potential complications. - Cardiovascular risk: avoid in patients with uncontrolled hypertension or recent thrombotic events. - Gastrointestinal safety: use with caution in those with a history of ulcers or bleeding. - Renal function: assess baseline kidney function and adjust use in chronic kidney disease. - Hepatic health: monitor liver enzymes in patients with liver disease. - Concomitant NSAIDs or anticoagulants: increase risk of bleeding. - Store at ambient temperature: keep below 25°C, in original packaging, protected from moisture.

Ketoprofen lysine can interact with several drug classes, altering efficacy or safety.

Major Interactions (Avoid): - Anticoagulants (e.g., warfarin): heightened risk of serious bleeding. - Selective COX‑2 inhibitors (e.g., celecoxib): additive gastrointestinal toxicity. - High‑dose aspirin (high > 325 mg/day).

Moderate Interactions (Monitor Closely): - ACE inhibitors (e.g., enalapril): may reduce antihypertensive effect. - Diuretics (e.g., furosemide): potential for reduced renal perfusion. - Lithium: increased serum lithium levels. - Methotrexate: decreased renal clearance, raising toxicity risk.