Okitask (Ketoprofen Lysine)

Ketoprofen lysine, the active ingredient in Okitask, is a non-steroidal anti-inflammatory drug (NSAID) presented as a solid oral dosage form for systemic use. It is commonly prescribed to manage pain and inflammation in adults.

GNH USA supplies Okitask as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Ketoprofen lysine is an NSAID that reduces inflammation and pain in several musculoskeletal conditions. - Osteoarthritis: alleviates joint pain and improves mobility. - Rheumatoid arthritis: decreases inflammation and joint swelling. - Acute musculoskeletal injury: provides short‑term relief of pain and inflammation. - Post‑operative pain: helps control pain after surgical procedures. - Dysmenorrhea: reduces menstrual‑related pelvic pain.

Ketoprofen lysine may cause a range of adverse reactions, most of which are mild to moderate and resolve after discontinuation.

Common Side Effects: - Gastrointestinal discomfort, such as dyspepsia or heartburn. - Nausea or vomiting. - Headache. - Dizziness. - Mild skin rash. - Elevated liver enzymes.

Serious or Rare Side Effects: - Peptic ulcer disease or gastrointestinal bleeding. - Severe skin reactions such as Stevens‑Johnson syndrome. - Renal impairment or acute kidney injury. - Hepatotoxicity with jaundice. - Anaphylactic or severe allergic reactions. - Cardiovascular events such as myocardial infarction or stroke.

When prescribing Ketoprofen lysine, clinicians should consider several safety aspects to minimise risk. - Gastrointestinal risk: assess history of ulcers or bleeding before use. - Cardiovascular caution: avoid in patients with uncontrolled hypertension or recent thrombotic events. - Renal function: monitor kidney parameters in patients with pre‑existing renal disease. - Hepatic monitoring: check liver function tests during prolonged therapy. - Drug interactions: review concomitant NSAIDs, anticoagulants and antihypertensives. - Store at ambient temperature: keep in the original container, protect from moisture and direct sunlight.

Ketoprofen lysine can interact with several drug classes, altering efficacy or safety.

Major Interactions (Avoid): - Anticoagulants (e.g., warfarin): increased risk of serious bleeding. - Other NSAIDs or COX‑2 inhibitors: heightened gastrointestinal toxicity. - Corticosteroids: additive risk of ulceration and bleeding.

Moderate Interactions (Monitor Closely): - ACE inhibitors or ARBs: may reduce antihypertensive effect and impair renal function. - Diuretics (especially thiazides): potential for reduced renal clearance. - Lithium: NSAIDs can increase lithium serum concentrations. - Methotrexate: decreased renal elimination may raise toxicity risk.