Okiact (Ketoprofen Lysine)

Ketoprofen lysine, the active ingredient in Okiact, is a non‑steroidal anti‑inflammatory drug presented as a oral tablet for systemic use. It is indicated for the relief of mild to moderate pain and inflammation in adults.

GNH USA supplies Okiact as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals and pharmacies worldwide.

Okiact (ketoprofen lysine) is a NSAID that reduces inflammation and pain in several musculoskeletal conditions. - Rheumatoid arthritis: helps reduce joint swelling, pain and stiffness. - Osteoarthritis: provides symptomatic relief of joint pain and improves mobility. - Acute musculoskeletal injury: alleviates pain and inflammation associated with sprains, strains and bruises. - Post‑operative pain: used as part of multimodal analgesia to control postoperative discomfort. - Dysmenorrhea: reduces menstrual pain and uterine cramping.

Ketoprofen lysine may cause a range of adverse reactions, most of which are mild and reversible.

Common Side Effects: - Gastrointestinal discomfort: nausea, dyspepsia or abdominal pain. - Headache: mild to moderate intensity. - Dizziness or light‑headedness. - Skin rash or mild itching. - Elevated liver enzymes.

Serious or Rare Side Effects: - Peptic ulcer disease or gastrointestinal bleeding. - Severe skin reactions such as Stevens‑Johnson syndrome. - Hepatotoxicity or marked liver injury. - Renal impairment or acute kidney injury. - Anaphylaxis or severe hypersensitivity reactions.

When using Okiact, consider the following safety measures: - Assess renal function: patients with impaired kidney function may need dose adjustment. - Monitor hepatic function: avoid use in active liver disease. - Evaluate cardiovascular risk: NSAIDs can increase blood pressure and thrombotic events. - Use gastro‑protective agents: consider co‑prescription in patients with ulcer risk. - Avoid in late pregnancy: NSAIDs are contraindicated in the third trimester. - Store at ambient temperature: keep in the original container, protect from moisture and direct sunlight.

Ketoprofen lysine can interact with several drug classes, altering efficacy or safety.

Major Interactions (Avoid): - Anticoagulants (e.g., warfarin): increased risk of serious bleeding. - Other NSAIDs or COX‑2 inhibitors: additive gastrointestinal toxicity. - High‑dose aspirin: heightened risk of gastric ulceration.

Moderate Interactions (Monitor Closely): - ACE inhibitors or ARBs: may reduce renal protective effects. - Diuretics (especially loop diuretics): potential for reduced kidney function. - Lithium: NSAIDs can increase serum lithium levels. - Methotrexate: reduced clearance may raise toxicity risk.