Europe — EMA
Oftasteril Alfa Intes (Povidone, Iodinated)
GNH USA supplies Oftasteril Alfa Intes (povidone‑iodine), a ophthalmic antiseptic for ocular surface antisepsis, pre‑ and post‑operative eye preparation
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What is Povidone, Iodinated?
Povidone‑iodine, the active ingredient in Oftasteril Alfa Intes, is an antiseptic, disinfectant presented as a solution for ocular use. It reduces microbial contamination on the eye surface and is employed before and after eye procedures and in minor eye injuries. GNH USA supplies Oftasteril Alfa Intes as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.
What is Povidone, Iodinated used for?
Oftasteril Alfa Intes, a povidone‑iodine ophthalmic antiseptic, provides antimicrobial protection for the eye in several clinical situations.
Ocular surface antisepsis: reduces microbial load prior to examinations or procedures. Pre‑ and post‑operative eye preparation: helps prevent surgical site infection. Minor eye injuries: minimizes risk of infection in superficial trauma.
What are the side effects of Povidone, Iodinated?
Adverse reactions may occur following ocular application of povidone‑iodine.
Common Side Effects: - Stinging or burning sensation at the site of application. - Redness of the conjunctiva or eyelid margin. - Excessive tearing or watery discharge. - Transient blurred vision. - Mild allergic contact dermatitis of the peri‑ocular skin. - Temporary irritation of the corneal epithelium.
Serious or Rare Side Effects: - Anaphylactic reaction or severe systemic allergy. - Corneal ulceration or persistent keratitis. - Severe pain or photophobia. - Vision loss due to ocular toxicity. - Significant intra‑ocular inflammation.
What precautions apply to Povidone, Iodinated?
Use of povidone‑iodine ophthalmic preparations requires careful consideration of patient factors and handling. - Allergy assessment: avoid in individuals with known iodine or povidone‑iodine hypersensitivity. - Pregnancy and lactation: limit use to situations where benefit outweighs potential risk, as safety data are limited. - Contact lens wearers: remove lenses before application and wait before reinserting. - Duration of use: limit to the shortest period necessary to achieve antisepsis. - Eye condition: avoid in patients with active corneal epithelial defects unless directed by a specialist. - Store at ambient temperature: keep in original container, protect from light and moisture.
What does Povidone, Iodinated interact with?
Povidone‑iodine may interact with other agents that affect iodine balance or ocular tolerance.
Major Interactions (Avoid): - Thyroid hormone therapy (levothyroxine): excess iodine may interfere with absorption. - Antithyroid medications (e.g., propylthiouracil): iodine load may reduce drug efficacy.
Moderate Interactions (Monitor Closely): - Concurrent use of other ocular antiseptics: may increase local irritation. - Preservative‑containing contact lens solutions: additive toxicity possible. - Systemic iodine supplements: may raise total iodine exposure.



