Europe — EMA
Oftaquix (Levofloxacin Hemihydrate)
Levofloxacin Hemihydrate, the active ingredient in Oftaquix, is a fluoroquinolone antibiotic presented as a tablet for oral use. It treats a variety of bacterial infections in adults and children when appropriate.
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What is Levofloxacin Hemihydrate?
Levofloxacin Hemihydrate, the active ingredient in Oftaquix, is a fluoroquinolone antibiotic presented as a tablet for oral use. It treats a variety of bacterial infections in adults and children when appropriate. GNH USA supplies Oftaquix as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.
GNH USA supplies Oftaquix as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.
What is Levofloxacin Hemihydrate used for?
Levofloxacin is a broad‑spectrum fluoroquinolone used for infections that involve bacterial pathogens.
- Community‑acquired pneumonia: helps eradicate the causative bacteria and improves respiratory function. - Acute bacterial sinusitis: reduces sinus inflammation and clears infection. - Uncomplicated urinary tract infection: eliminates uropathogens and relieves urinary symptoms. - Skin and soft‑tissue infections: targets common skin pathogens to promote healing. - Chronic bronchitis exacerbations: controls bacterial overgrowth during flare‑ups. - Gonorrhoea (susceptible strains): eradicates Neisseria gonorrhoeae and prevents spread.
What are the side effects of Levofloxacin Hemihydrate?
Levofloxacin, like other fluoroquinolones, may cause a range of adverse reactions.
Common Side Effects: - Nausea or vomiting: mild gastrointestinal upset. - Diarrhea: loose stools that may be self‑limiting. - Headache: transient cranial discomfort. - Dizziness: occasional light‑headedness. - Photosensitivity: increased skin sensitivity to sunlight. - Abdominal pain: cramping or discomfort in the stomach area.
Serious or Rare Side Effects: - Tendon rupture or tendinitis: pain or swelling in tendons, especially the Achilles. - QT interval prolongation: irregular heart rhythm detectable on ECG. - Severe allergic reaction: hives, swelling, or breathing difficulty. - Central nervous system effects: seizures or severe confusion. - Clostridioides difficile infection: persistent watery diarrhea. - Liver enzyme elevation: abnormal liver function tests.
What precautions apply to Levofloxacin Hemihydrate?
Levofloxacin should be used with caution in patients with certain medical conditions and drug sensitivities.
- Renal impairment: dose adjustment may be required. - History of tendon disorders: avoid use if previous tendon injury occurred. - Cardiac arrhythmia risk: monitor QT interval in susceptible individuals. - Seizure history: use cautiously as it may lower seizure threshold. - Pregnancy and lactation: only if clearly needed. - Store at below 25°C: keep in the original packaging, protect from moisture and light.
What does Levofloxacin Hemihydrate interact with?
Levofloxacin can interact with several medicines, altering its effectiveness or safety profile.
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