Oftaquix (Levofloxacin Hemihydrate)

Levofloxacin Hemihydrate, the active ingredient in Oftaquix, is a fluoroquinolone antibiotic presented as a solid oral dosage form for systemic use. It treats bacterial infections in adults and children when prescribed by a qualified healthcare professional.

GNH USA supplies Oftaquix as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Levofloxacin is a broad‑spectrum antibacterial agent used for infections that involve the respiratory, urinary and skin structures. - Community‑acquired pneumonia: helps eradicate the causative bacteria and improve clinical recovery. - Uncomplicated urinary tract infection: eliminates the infecting organism and reduces symptoms. - Acute bacterial skin and skin‑structure infections: clears the pathogen and promotes lesion healing.

Levofloxacin may cause a range of adverse reactions, most of which are mild and reversible.

Common Side Effects: - Nausea: mild stomach upset that often resolves without treatment. - Diarrhea: loose stools that may be self‑limiting. - Headache: transient cranial discomfort. - Dizziness: occasional light‑headedness. - Photosensitivity: increased skin sensitivity to sunlight.

Serious or Rare Side Effects: - Tendon rupture: sudden pain or loss of function in tendons, especially the Achilles. - QT prolongation: abnormal heart rhythm detectable on ECG. - Severe allergic reaction: rash, swelling, or breathing difficulty requiring urgent care. - Peripheral neuropathy: tingling or numbness in extremities. - Clostridioides difficile colitis: severe diarrhea with abdominal pain.

Levofloxacin should be used with caution in specific clinical situations and patient groups. - Renal impairment: dose adjustment may be required based on kidney function. - History of tendon disorders: avoid use if previous tendon injury related to fluoroquinolones. - Cardiac arrhythmias: monitor patients with known QT‑interval prolongation. - Pregnancy and lactation: only prescribe if the benefit outweighs potential risk. - Concomitant CNS active drugs: observe for increased risk of seizures. - Store at below 25°C: keep in the original container, protect from moisture and direct sunlight.

Levofloxacin can affect the plasma concentrations of several co‑administered medicines, requiring attention to dosing and monitoring.

Major Interactions (Avoid): - Antacids containing aluminum or magnesium: reduce levofloxacin absorption. - Warfarin: may increase anticoagulant effect and bleeding risk. - Non‑steroidal anti‑inflammatory drugs (NSAIDs): heightened risk of CNS stimulation.

Moderate Interactions (Monitor Closely): - Theophylline: possible increase in serum levels leading to toxicity. - Cyclosporine: may raise levofloxacin concentrations. - Oral hypoglycemic agents: potential for altered blood glucose control.