Oftaquix (Levofloxacin Hemihydrate)

Levofloxacin, the active ingredient in Oftaquix, is a Fluoroquinolone antibiotic presented as an oral tablet for systemic use. It treats a range of bacterial infections in adults and children when prescribed by a qualified healthcare professional.

GNH USA supplies Oftaquix as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Levofloxacin is a broad‑spectrum fluoroquinolone used to treat infections caused by susceptible bacteria.

- Community‑Acquired Pneumonia: eradicates the typical bacterial pathogens and improves respiratory function. - Acute Bacterial Sinusitis: reduces sinus inflammation and clears the infection. - Acute Exacerbation of Chronic Bronchitis: shortens symptom duration and prevents complications. - Uncomplicated Urinary Tract Infection: eliminates uropathogens and resolves urinary symptoms. - Skin and Soft‑Tissue Infections: controls bacterial spread and promotes wound healing. - Acute Bacterial Prostatitis: penetrates prostatic tissue to eradicate infection.

Levofloxacin may cause a variety of adverse reactions, ranging from mild to severe.

Common Side Effects: - Nausea: mild gastrointestinal upset. - Diarrhea: loose stools, sometimes watery. - Headache: transient cranial discomfort. - Dizziness: occasional light‑headedness. - Insomnia: difficulty falling or staying asleep. - Rash: mild skin erythema.

Serious or Rare Side Effects: - Tendon rupture: especially Achilles, often linked to sudden activity. - QT interval prolongation: may precipitate cardiac arrhythmias. - Severe hypersensitivity: including Stevens‑Johnson syndrome. - Peripheral neuropathy: persistent numbness or tingling. - Hepatotoxicity: elevated liver enzymes or jaundice. - Central nervous system effects: seizures or psychosis.

Levofloxacin should be used with caution in specific clinical situations.

- Hypersensitivity: avoid in patients with known fluoroquinolone allergy. - Tendon disorders: discontinue if tendon pain or swelling occurs. - Cardiac risk: monitor QT interval in patients with arrhythmia history. - Central nervous system: use carefully in patients with seizures or psychiatric disorders. - Pregnancy and lactation: avoid unless benefits outweigh potential risks. - Renal impairment: adjust dose based on renal function. - Store at room temperature: keep in original container, protect from moisture and light.

Levofloxacin can interact with several medicines, altering efficacy or safety.

Major Interactions (Avoid): - Antacids or supplements containing magnesium/aluminum/iron: reduce levofloxacin absorption. - Warfarin: may increase INR and bleeding risk. - Theophylline: heightened risk of seizures and cardiac toxicity. - Cyclosporine: increased serum levels of both drugs. - NSAIDs (e.g., ibuprofen): heightened risk of CNS stimulation and seizures.

Moderate Interactions (Monitor Closely): - Oral contraceptives: reduced contraceptive effectiveness. - Diabetic agents: potential for altered blood glucose control. - Corticosteroids: increased risk of tendon rupture. - Diuretics: possible electrolyte disturbances. - Antidepressants (SSRIs): monitor for QT prolongation.