Oftaquix (Levofloxacin Hemihydrate)

Levofloxacin Hemihydrate, the active ingredient in Oftaquix, is a fluoroquinolone antibiotic presented as a tablet for oral use. It treats a variety of bacterial infections in adults and children when appropriate.

GNH USA supplies Oftaquix as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Levofloxacin is a broad‑spectrum antibacterial agent used for infections affecting several organ systems.

- Community‑acquired bacterial pneumonia: helps achieve clinical cure and bacterial eradication. - Acute bacterial sinusitis: reduces symptoms and clears the infecting pathogen. - Uncomplicated urinary tract infection: provides bacterial eradication and symptom relief. - Skin and soft‑tissue infections: assists in resolving infection and preventing spread. - Chronic bronchitis exacerbations: aids in bacterial clearance and improves airflow. - Gonorrhoea (single‑dose therapy): offers microbiological cure.

Levofloxacin may cause a range of adverse reactions, most of which are mild and self‑limiting.

Common Side Effects: - Nausea: mild stomach upset often reported. - Diarrhea: loose stools that usually resolve without treatment. - Headache: transient cranial discomfort. - Dizziness: occasional light‑headedness. - Photosensitivity: increased skin sensitivity to sunlight. - Abdominal pain: cramping or discomfort in the stomach area.

Serious or Rare Side Effects: - Tendon rupture: sudden tendon pain or rupture, especially in the Achilles. - QT prolongation: irregular heart rhythm detectable on ECG. - Severe allergic reaction: rash, swelling, or difficulty breathing. - Clostridioides difficile infection: persistent watery diarrhea. - Peripheral neuropathy: tingling or numbness in extremities. - Hepatotoxicity: elevated liver enzymes or jaundice.

Levofloxacin should be used with caution in patients with specific risk factors and medical histories.

- Renal impairment: dose adjustment may be required based on kidney function. - History of tendon disorders: avoid use if previous tendon inflammation or rupture occurred. - Cardiac arrhythmias: monitor QT interval in patients with known prolongation. - Seizure disorders: use cautiously as it may lower seizure threshold. - Pregnancy and lactation: only prescribe if benefits outweigh potential risks. - Store at below 25°C: keep in the original packaging, protect from moisture and direct sunlight.

Levofloxacin can interact with several medicines, altering its efficacy or safety profile.

Major Interactions (Avoid): - Antacids containing aluminum or magnesium: reduce levofloxacin absorption. - Warfarin: may increase anticoagulant effect and bleeding risk. - NSAIDs (e.g., ibuprofen): heighten risk of central nervous system stimulation.

Moderate Interactions (Monitor Closely): - Theophylline: may increase serum theophylline concentrations. - Cyclosporine: potential for increased nephrotoxicity. - Oral hypoglycemics: may enhance glucose‑lowering effect.