Oftaquix (Levofloxacin Hemihydrate)

Levofloxacin Hemihydrate, the active ingredient in Oftaquix, is a fluoroquinolone antibiotic presented as a solid dosage form for oral use. It treats bacterial infections in adults and children when prescribed by a healthcare professional.

GNH USA supplies Oftaquix as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Levofloxacin is a broad‑spectrum antibacterial agent used in infections of various organ systems. - Community‑acquired pneumonia: helps eradicate the causative bacteria and improve respiratory symptoms. - Uncomplicated urinary tract infection: eliminates the uropathogen and resolves urinary discomfort. - Acute bacterial skin and skin‑structure infections: clears the infection and promotes wound healing.

Levofloxacin may cause a range of adverse reactions, most of which are mild and reversible.

Common Side Effects: - Nausea: mild stomach upset often reported. - Diarrhea: loose stools occurring during therapy. - Headache: transient head discomfort. - Dizziness: occasional light‑headedness. - Photosensitivity: increased skin sensitivity to sunlight.

Serious or Rare Side Effects: - Tendon rupture: sudden tendon pain or rupture, especially in the Achilles. - QT interval prolongation: heart rhythm changes detectable on ECG. - Severe allergic reaction: rash, swelling, or breathing difficulty. - Peripheral neuropathy: numbness or tingling in extremities. - Clostridioides difficile infection: severe colitis following antibiotic use.

Levofloxacin should be used with caution in patients with specific risk factors and medical histories. - Renal impairment: dose adjustment may be required. - History of tendon disorders: avoid use or monitor closely. - Cardiac arrhythmias: assess QT interval before initiating therapy. - Pregnancy and lactation: only use if clearly needed after risk‑benefit evaluation. - Concomitant use of corticosteroids: increase monitoring for tendon toxicity. - Store below 25°C: keep in the original container, protect from moisture and direct sunlight.

Levofloxacin can interact with several medicines, altering efficacy or safety.

Major Interactions (Avoid): - Antacids containing aluminum or magnesium: reduce levofloxacin absorption. - Warfarin: may increase anticoagulant effect and bleeding risk. - Non‑steroidal anti‑inflammatory drugs (NSAIDs): heighten risk of central nervous system stimulation.

Moderate Interactions (Monitor Closely): - Theophylline: may increase plasma concentrations of the bronchodilator. - Cyclosporine: potential for increased nephrotoxicity. - Diabetic agents (sulfonylureas, insulin): may cause hypoglycaemia. - Oral contraceptives: possible reduction in contraceptive effectiveness.