Europe — EMA
Oftaquix (Levofloxacin Hemihydrate)
GNH USA supplies Oftaquix (Levofloxacin), a fluoroquinolone antibacterial for eye infections like conjunctivitis and keratitis. Request a quote for supply.
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What is Levofloxacin Hemihydrate?
Levofloxacin, the active ingredient in Oftaquix, is a fluoroquinolone presented as an ophthalmic solution for ocular use. It treats bacterial eye infections such as conjunctivitis and keratitis in both adult and pediatric patients.
GNH USA supplies Oftaquix as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to EU GMP standards and provides regulatory documentation for importers. Its global logistics network ensures timely delivery across multiple continents while maintaining product integrity through validated temperature‑controlled packaging.
What is Levofloxacin Hemihydrate used for?
Oftaquix (levofloxacin) is used to treat bacterial infections of the eye, targeting common ocular pathogens.
Bacterial conjunctivitis: reduces bacterial load and accelerates symptom resolution. Bacterial keratitis: eradicates causative organisms and promotes corneal healing. Corneal ulcer: provides broad‑spectrum coverage to prevent progression and facilitate epithelial regeneration.
What are the side effects of Levofloxacin Hemihydrate?
Oftaquix may cause ocular and systemic adverse reactions, most of which are mild and transient.
Common Side Effects: - Transient burning or stinging sensation upon instillation. - Mild conjunctival hyperemia (redness). - Temporary blurred vision or foreign‑body feeling. - Mild itching or tearing.
Serious or Rare Side Effects: - Corneal epithelial toxicity or ulceration. - Severe allergic reactions including angioedema, Stevens‑Johnson syndrome or toxic epidermal necrolysis. - Systemic tendon rupture or tendonitis, especially in patients on corticosteroids.
What precautions apply to Levofloxacin Hemihydrate?
Before prescribing Oftaquix, consider the following precautions to ensure safe use. - Hypersensitivity: discontinue if patient shows signs of allergic reaction. - Corneal disease: avoid in patients with active corneal epithelial defects unless benefits outweigh risks. - Pregnancy and lactation: use only if clearly needed, as safety data are limited. - Concurrent systemic fluoroquinolone therapy: monitor for additive toxicity. - Drug interactions: be cautious with NSAIDs or corticosteroids that may increase risk of tendon injury. - Store at ambient temperature: keep below 25 °C, protect from moisture and light in original container.
What does Levofloxacin Hemihydrate interact with?
Levofloxacin can interact with other medicines, affecting its efficacy or safety.
Major Interactions (Avoid): - Antacids, iron or zinc supplements: chelate levofloxacin and markedly reduce ocular absorption. - Warfarin: may potentiate anticoagulant effect, increasing bleeding risk. - Systemic corticosteroids: increase risk of tendon rupture.
Moderate Interactions (Monitor Closely): - Non‑steroidal anti‑inflammatory drugs (NSAIDs): may enhance risk of corneal toxicity. - Other fluoroquinolones: additive toxicity, avoid concurrent use. - Diabetes medications: monitor blood glucose as fluoroquinolones can affect glycemic control.



