Oftan Flurekain (Oxybuprocaine Hydrochloride, Fluorescein Sodium)

Oxybuprocaine Hydrochloride / Fluorescein Sodium, the active ingredient in Oftan Flurekain, is a local anesthetic presented as an ocular solution for ocular use. It provides reversible surface anesthesia for diagnostic eye procedures and stains the corneal epithelium to highlight defects. GNH USA supplies Oftan Flurekain as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Oftan Flurekain, an ophthalmic local anesthetic and corneal stain, is employed in ocular diagnostic and therapeutic procedures. - Tonometry: provides temporary corneal anesthesia to facilitate accurate intra‑ocular pressure measurement. - Slit‑lamp examination: anesthetizes the ocular surface allowing detailed examination without discomfort. - Corneal staining: fluorescein component highlights epithelial defects, abrasions or foreign bodies for visualization.

Common Side Effects: - Burning or stinging sensation on instillation. - Transient redness or conjunctival hyperemia. - Increased tearing or watery discharge. - Mild blurred vision lasting a few minutes. - Temporary eyelid swelling. - Mild allergic conjunctivitis.

Serious or Rare Side Effects: - Corneal epithelial toxicity or ulceration. - Severe allergic reaction including anaphylaxis. - Persistent corneal inflammation or keratitis. - Stevens‑Johnson syndrome or toxic epidermal necrolysis. - Vision loss due to corneal damage. - Intra‑ocular inflammation (uveitis).

Before using Oftan Flurekain, consider the following precautions: - Allergy assessment: avoid in patients with known hypersensitivity to oxybuprocaine, fluorescein or related compounds. - Contact lens wear: remove lenses prior to administration to prevent drug retention. - Pre‑existing ocular surface disease: use with caution in patients with corneal ulcers or severe dry eye. - Pediatric use: limit to supervised administration; dosing is determined by the clinician. - Pregnancy and lactation: safety not established; weigh benefits against potential risks. - Store at room temperature: keep in original container, protect from light and moisture.

Oftan Flurekain may interact with other ophthalmic agents. Major Interactions (Avoid): - Concurrent use with other topical ocular anesthetics may cause additive toxicity. - Combination with ophthalmic solutions containing preservatives that increase irritation. - Simultaneous use of multiple fluorescein‑containing products may lead to overstaining. Moderate Interactions (Monitor Closely): - Co‑administration with anti‑inflammatory eye drops may alter drug absorption. - Use with beta‑blocker eye drops may affect intra‑ocular pressure measurement accuracy. - Combination with ocular antibiotics may increase risk of corneal toxicity.