Europe — EMA
Oftan Chlora (Chloramphenicol)
Chloramphenicol, the active ingredient in Oftan Chlora, is an antibiotic presented as a topical ophthalmic solution for ocular use. It treats bacterial eye infections such as conjunctivitis and keratitis in adults and…
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What is Chloramphenicol?
Chloramphenicol, the active ingredient in Oftan Chlora, is an antibiotic presented as a topical ophthalmic solution for ocular use. It treats bacterial eye infections such as conjunctivitis and keratitis in adults and children. GNH USA supplies Oftan Chlora as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals and pharmacies worldwide.
GNH USA supplies Oftan Chlora as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals and pharmacies worldwide.
What is Chloramphenicol used for?
Chloramphenicol is used for bacterial eye infections, acting on the ocular surface to inhibit bacterial growth.
- Conjunctivitis: reduces bacterial load and speeds up symptom relief. - Keratitis: helps eradicate causative bacteria and supports corneal healing. - Blepharitis: controls bacterial colonisation on the eyelid margin. - Post‑surgical prophylaxis: lowers risk of infection after ocular surgery. - Traumatic corneal ulcer: assists in eliminating infection and promoting tissue repair.
What are the side effects of Chloramphenicol?
Chloramphenicol ophthalmic solution may cause local and systemic adverse reactions.
Common Side Effects: - Burning sensation: mild irritation upon instillation. - Redness: transient conjunctival hyperemia. - Tearing: increased lacrimation. - Foreign‑body sensation: feeling of grit. - Blurred vision: temporary visual disturbance. - Pruritus: itching of the ocular surface.
Serious or Rare Side Effects: - Allergic contact dermatitis: erythema, swelling, and itching. - Stevens‑Stevenson disease: rare severe skin reaction. - Bone marrow suppression: aplastic anemia (very rare). - Vision loss: due to severe ocular inflammation. - Systemic toxicity: nausea, headache if absorbed in large amounts. - Endophthalmitis: intra‑ocular infection despite therapy.
What precautions apply to Chloramphenicol?
When using Chloramphenicol ophthalmic solution, follow safety guidelines to minimise risks.
- Indication verification: ensure the product is prescribed for a bacterial eye infection. - Duration of therapy: limit use to the prescribed period to avoid resistance. - Monitoring: watch for signs of allergic reaction or worsening infection. - Contraindications: avoid in patients with known hypersensitivity to chloramphenicol or related compounds. - Pregnancy and lactation: use only if clearly needed, after risk‑benefit assessment. - Store at ambient temperature: keep in the original container, protect from light and moisture.
What does Chloramphenicol interact with?
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