Oftacortal (Dexamethasone Sodium Phosphate)

Dexamethasone sodium phosphate, the active ingredient in Oftacortal, is a corticosteroid presented as a sterile injectable solution for ophthalmic use. It treats ocular inflammation and allergic reactions in patients requiring rapid anti‑inflammatory therapy. GNH USA supplies Oftacortal as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals and ophthalmology clinics worldwide.

Oftacortal, a corticosteroid acting on inflammatory pathways in the eye, is used for several ophthalmic conditions: - Post‑operative inflammation: Reduces swelling and pain after eye surgery. - Anterior uveitis: Controls intra‑ocular inflammation in the anterior segment. - Allergic conjunctivitis: Relieves redness, itching and swelling caused by allergens. - Ocular edema edema: Decreases fluid accumulation in the cornea and anterior chamber.

Adverse reactions to dexamethasone sodium phosphate in ophthalmic preparations are generally related to local irritation and systemic steroid exposure.

Common Side Effects: - Eye irritation: Burning or stinging sensation. - Increased intra‑ocular pressure: Transient rise detectable on exam. - Blurred vision: Temporary visual disturbance. - Conjunctival hyperemia: Redness of the eye surface.

Serious or Rare Side Effects: - Secondary ocular infection: Bacterial or fungal infection due to immunosuppression. - Cataract formation: Accelerated lens opacity with prolonged use. - Glaucoma: Persistent elevation of intra‑ocular pressure leading to optic nerve damage. - Systemic adrenal suppression: Reduced endogenous cortisol production.

When using Oftacortal, clinicians should consider several safety measures: - Monitor intra‑ocular pressure: Regular checks during therapy. - Assess infection risk: Avoid use in active ocular infections unless combined with antimicrobial therapy. - Evaluate systemic steroid exposure: Consider patient history of diabetes or hypertension. - Use lowest effective dose: Limit duration to reduce adverse effects. - Store at ambient temperature: Keep below 25°C, in original packaging, protected from moisture.

Oftacortal may interact with other ophthalmic and systemic medications. Awareness of these interactions helps maintain therapeutic effectiveness.

Major Interactions (Avoid): - Antifungal s : Potential P P   t  

Moderate  t  t  t  t