Oftacilox (Ciprofloxacin Hydrochloride)

Ciprofloxacin, the active ingredient in Oftacilox, is a fluoroquinolone antibiotic presented as an ophthalmic solution for topical ocular use. It provides broad‑spectrum coverage against Gram‑negative and Gram‑positive bacteria that cause eye infections, and is indicated for the treatment of bacterial conjunctivitis, keratitis, and other superficial ocular infections in both adult and pediatric patients.

GNH USA supplies Oftacilox as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Oftacilox (ciprofloxacin) is an ophthalmic fluoroquinolone used to treat bacterial infections of the eye. - Bacterial conjunctivitis: reduces bacterial load and resolves inflammation of the conjunctiva. - Bacterial keratitis: eradicates causative organisms and promotes corneal healing. - Post‑operative ocular prophylaxis: prevents infection after eye surgery or invasive procedures.

Common Side Effects: - Eye irritation or burning sensation. - Redness of the conjunctiva. - Transient blurred vision. - Increased tearing or discharge. - Foreign body sensation.

Serious or Rare Side Effects: - Allergic reactions such as swelling, rash, or hives. - Corneal ulceration or perforation. - Stevens‑Johnson syndrome or toxic epidermal necrolysis. - Severe eye pain with vision loss. - Persistent or worsening infection despite therapy.

Before using Oftacilox, consider the following precautions: - Allergy assessment: verify no known hypersensitivity to fluoroquinolones or any component of the formulation. - Contact lens wearers: avoid use unless advised by an eye care professional, as lenses may retain the drug and increase irritation. - Pregnancy and lactation: use only if the potential benefit justifies the potential risk to the fetus or infant. - Systemic exposure: monitor for systemic fluoroquinolone effects if used for prolonged periods or on large ocular surfaces. - Storage: Store at room temperature below 25°C: keep in the original container, protect from light and moisture.

Oftacilox may interact with other agents when used concurrently. Major Interactions (Avoid): - Systemic fluoroquinolones: concurrent use may increase systemic exposure and risk of systemic side effects. - Live vaccines: avoid administration of live vaccines while using the product due to potential immunomodulation.

Moderate Interactions (Monitor Closely): - Topical corticosteroids: may mask signs of infection and delay healing. - Preservative‑containing contact lens solutions: can increase ocular irritation. - Other ophthalmic antibiotics: concurrent use should be guided by a clinician to prevent antagonism or additive toxicity.