Ofloxin (Ofloxacin)

Ofloxacin, the active ingredient in Ofloxin, is a fluoroquinolone presented as an oral tablet for systemic use. It treats bacterial infections in adults and children when prescribed, targeting a range of urinary, respiratory, skin, prostate and sexually transmitted infections. It is effective against a broad spectrum of Gram‑negative and Gram‑positive bacteria.

GNH USA supplies Ofloxin as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, with quality assurance, regulatory compliance and reliable logistics for global distribution, ensuring consistent supply and adherence to international pharmacopeial standards.

Ofloxin (ofloxacin) is a fluoroquinolone antibacterial used to treat infections in various organ systems.

- Urinary tract infection: eradicates susceptible bacteria, relieving symptoms and preventing complications. - Respiratory tract infection: treats acute infections such as bronchitis and pneumonia caused by susceptible organisms. - Skin and soft tissue infection: resolves cellulitis, abscesses and wound infections due to susceptible pathogens. - Prostatitis: eliminates bacterial infection of the prostate, improving urinary function and pain. - Sexually transmitted infections: combats infections like gonorrhea caused by susceptible strains.

Ofloxin may be associated with a range of adverse reactions, varying from mild to serious.

Common Side Effects: - Nausea: mild to moderate stomach upset. - Diarrhea: loose stools, sometimes watery. - Headache: mild to moderate intensity. - Dizziness: transient light‑headedness. - Abdominal pain: cramping or discomfort. - Rash: mild skin erythema.

Serious or Rare Side Effects: - Tendon rupture: especially Achilles, requiring immediate medical attention. - QT interval prolongation: may lead to cardiac arrhythmias. - Severe allergic reactions: including anaphylaxis, angioedema. - Clostridioides difficile infection: severe colitis. - Hepatic dysfunction: elevated liver enzymes or hepatitis. - Peripheral neuropathy: numbness or tingling in extremities.

When prescribing Ofloxin, clinicians should consider several safety aspects. - Renal impairment: adjust dose as recommended by the prescriber. - History of tendon disorders: avoid use or monitor closely for tendon pain. - QT prolongation risk: avoid in patients with known cardiac arrhythmias. - Pregnancy and lactation: use only if benefits outweigh potential risks. - Drug interactions: review concomitant medications for potential interactions. - Store at ambient temperature: keep below 25 °C, in original packaging, protected from moisture.

Ofloxin can interact with other medicines, requiring careful management.

Major Interactions (Avoid): - Antacids containing aluminum, magnesium, calcium, or iron: may markedly reduce ofloxacin absorption. - Warfarin: may enhance anticoagulant effect, increasing bleeding risk. - Other QT‑prolonging agents: combined use can increase risk of serious cardiac arrhythmias.

Moderate Interactions (Monitor Closely): - Non‑steroidal anti‑inflammatory drugs (NSAIDs): may increase risk of central nervous system stimulation. - CYP450 inducers such as rifampin: may lower ofloxacin plasma concentrations, reducing efficacy.