Ofloxacine Teva

Ofloxacin, the active ingredient in Ofloxacine Teva, is a fluoroquinolone antibiotic presented as oral tablets for systemic use. It treats a range of bacterial infections in adult and pediatric patients when prescribed by a qualified health professional.

GNH USA supplies Ofloxacine Teva as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Ofloxacin is a broad‑spectrum fluoroquinolone used to treat infections of several organ systems.

- Uncomplicated urinary tract infection: eradicates susceptible uropathogens and resolves dysuria and frequency. - Acute bacterial sinusitis: eliminates the causative bacteria and improves sinus drainage. - Acute exacerbation of chronic bronchitis: reduces bacterial load and eases cough and sputum production. - Skin and soft‑tissue infection: clears susceptible Staphylococcus and Streptococcus species, promoting wound healing. - Gonorrhea: rapidly kills Neisseria gonorrhoeae, preventing disease progression.

Common Side Effects: - Nausea: mild to moderate upset stomach. - Diarrhea: loose stools, sometimes watery. - Headache: transient cranial discomfort. - Dizziness: occasional light‑headed sensation. - Abdominal pain: cramping or discomfort. - Rash: mild skin erythema.

Serious or Rare Side Effects: - Tendon rupture: sudden pain and loss of function, especially in the Achilles tendon. - QT interval prolongation: may lead to cardiac arrhythmias. - Severe allergic reactions: anaphylaxis, angioedema, or bronchospasm. - Clostridioides difficile‑associated diarrhea: severe colitis requiring medical attention. - Stevens‑Johnson syndrome: extensive skin blistering and mucosal involvement. - Hepatic dysfunction: elevated liver enzymes or jaundice.

Before initiating therapy, clinicians should evaluate patient‑specific risk factors and monitor for adverse events. - Assess renal function: adjust dosing in patients with impaired clearance. - Avoid in patients with known hypersensitivity to fluoroquinolones. - Monitor for tendon pain or inflammation: discontinue if tendonitis or rupture occurs. - Use with caution during pregnancy or lactation: only if benefits outweigh potential risks. - Store at ambient temperature below 25°C: keep in the original pack, protect from moisture.

Ofloxacine Teva may interact with several medicines; careful review is required.

Major Interactions (Avoid): - Antacids containing magnesium or aluminum: markedly reduce ofloxacin absorption. - Tizanidine: co‑administration can cause profound hypotension and sedation. - Warfarin: may potentiate anticoagulant effect and increase bleeding risk. - Concurrent use with other fluoroquinolones: additive toxicity, especially tendon and CNS effects.

Moderate Interactions (Monitor Closely): - NSAIDs: may increase central nervous system stimulation and seizure risk. - Theophylline: ofloxacin can raise plasma theophylline concentrations, requiring dose adjustment. - Ciprofloxacin: combined use may enhance QT‑interval prolongation.