Ofloxacine Sandoz

Ofloxacin, the active ingredient in Ofloxacine Sandoz, is a fluoroquinolone antibiotic presented as a tablet for oral use. It treats a variety of bacterial infections in adults and children, including urinary, respiratory and skin infections.\n\nGNH India supplies Ofloxacine Sandoz as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Ofloxacin is a broad‑spectrum fluoroquinolone used to manage bacterial infections across several organ systems.\n\n- Urinary tract infection: eradicates susceptible Gram‑negative and Gram‑positive bacteria, promoting rapid symptom relief.\n- Acute bacterial sinusitis: reduces bacterial load, aiding recovery of sinus mucosa.\n- Acute exacerbation of chronic bronchitis: targets common respiratory pathogens, improving airflow and cough.\n- Skin and soft‑tissue infection: combats Staphylococcus and Streptococcus species, facilitating wound healing.\n- Uncomplicated gonorrhoea: eliminates Neisseria gonorrhoeae, preventing disease progression.

Common Side Effects:\n- Nausea\n- Diarrhoea\n- Headache\n- Dizziness\n- Abdominal pain\n- Rash\n\nSerious or Rare Side Effects:\n- Tendon rupture or tendinitis\n- QT interval prolongation leading to arrhythmia\n- Severe allergic reactions (anaphylaxis)\n- Clostridioides difficile‑associated diarrhoea\n- Hepatic dysfunction\n- Photosensitivity

Before prescribing Ofloxacine Sandoz, consider the following precautions.\n\n- Renal impairment: adjust dose according to renal function.\n- History of tendon disorders: avoid use or monitor closely for tendon pain.\n- Pregnancy and lactation: contraindicated unless benefits outweigh risks.\n- Concomitant QT‑prolonging drugs: monitor cardiac rhythm.\n- Use in children: follow pediatric dosing guidelines.\n- Store at room temperature: keep in original container, protect from moisture and light.

Ofloxacin may interact with several medicines; review patient medication lists carefully.\n\nMajor Interactions (Avoid):\n- Tizanidine: co‑administration can cause severe hypotension.\n- Non‑steroidal anti‑inflammatory drugs (NSAIDs): increased risk of central nervous system stimulation.\n- Antacids containing magnesium or aluminium: reduce Ofloxacin absorption.\n\nModerate Interactions (Monitor Closely):\n- Other fluoroquinolones (e.g., ciprofloxacin): additive QT prolongation risk.\n- Warfarin: may enhance anticoagulant effect, requiring INR monitoring.\n- Theophylline: Ofloxacin can increase plasma theophylline levels, necessitating dose adjustment.