Ofloxacine Eg

Ofloxacin, the active ingredient in Ofloxacine Eg, is a fluoroquinolone antibiotic presented as an oral tablet for systemic use. It treats a range of bacterial infections in adults and children as prescribed.

GNH USA supplies Ofloxacine Eg as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Ofloxacin is indicated for infections caused by susceptible bacteria affecting various organ systems.

- Urinary tract infection: eradicates susceptible uropathogens and resolves dysuria and frequency. - Acute bacterial sinusitis: eliminates causative organisms and improves nasal congestion. - Community‑acquired lower respiratory tract infection: clears pathogens responsible for bronchitis and pneumonia. - Skin and soft‑tissue infection: treats cellulitis and wound infections caused by susceptible strains. - Gonorrhea (uncomplicated): provides bactericidal activity against Neisseria gonorrhoeae.

Adverse reactions to Ofloxacin can range from mild to severe and may vary with patient factors.

Common Side Effects: - Nausea: mild to moderate gastrointestinal upset. - Diarrhea: loose stools, occasionally watery. - Headache: transient cranial discomfort. - Dizziness: sensation of light‑headedness. - Abdominal pain: cramp‑like discomfort. - Rash: mild skin erythema.

Serious or Rare Side Effects: - Tendon rupture: sudden tendon pain or rupture, especially Achilles. - QT interval prolongation: risk of cardiac arrhythmias. - Severe allergic reactions: anaphylaxis, Stevens‑Johnson syndrome. - Clostridioides difficile‑associated diarrhea: severe colitis. - Hepatic dysfunction: elevated liver enzymes, jaundice. - Peripheral neuropathy: tingling or numbness in extremities.

Before prescribing Ofloxacin, clinicians should consider several safety aspects.

- Renal impairment: dose adjustment may be required in reduced kidney function. - History of tendon disorders: avoid use in patients with prior tendon injury. - QT prolongation risk: monitor ECG in patients with cardiac arrhythmia history. - Pregnancy and lactation: reserve for situations where benefits outweigh potential risks. - Concomitant medications: review for interactions that may increase toxicity. - Store at ambient temperature: keep in original packaging, protect from moisture and direct sunlight.

Ofloxacin may interact with other medicines, altering efficacy or safety.

Major Interactions (Avoid): - Antacids containing aluminum or magnesium: reduce Ofloxacin absorption. - NSAIDs (e.g., ibuprofen): increase risk of central nervous system adverse effects. - Systemic corticosteroids: heighten risk of tendon rupture. - Other fluoroquinolones (e.g., ciprofloxacin): additive QT prolongation. - Warfarin: may enhance anticoagulant effect and increase bleeding risk.

Moderate Interactions (Monitor Closely): - Theophylline: Ofloxacin can raise plasma theophylline concentrations. - Cyclosporine: increased cyclosporine levels may occur. - Diabetes medications (e.g., insulin): possible alteration of glucose control.