GNH USA

Europe — EMA

Ofloxacine Biogaran

GNH USA supplies Ofloxacine Biogaren (Ofloxacin), a fluoroquinolone antibiotic for urinary, respiratory and skin infections.

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What is Ofloxacin?

Ofloxacin, the active ingredient in Ofloxacine Biogaren, is a fluoroquinolone antibiotic presented as a tablet for oral use. It treats a variety of bacterial infections in adults and children when prescribed by a healthcare professional.

GNH USA supplies Ofloxacine Biogaren as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

What is Ofloxacin used for?

Ofloxacine Biogaren is a broad‑spectrum antibacterial agent that acts on Gram‑negative and Gram‑positive pathogens in several organ systems. - Urinary tract infection: helps reduce bacterial load and resolves infection symptoms. - Respiratory tract infection: aids in clearing the causative bacteria and improves breathing comfort. - Skin and soft‑tissue infection: assists in eradic the infecting organisms and promotes lesion healing.

What are the side effects of Ofloxacin?

Ofloxacine Biogaren may cause a range of adverse reactions, most of which are mild and reversible.

Common Side Effects: - Nausea: mild stomach upset often reported. - Diarrhea: loose stools occurring during treatment. - Headache: transient head pain without neurological signs. - Dizziness: brief episodes of light‑headedness. - Rash: skin redness or mild itching. - Photosensitivity: increased skin sensitivity to sunlight.

Serious or Rare Side Effects: - Tendon rupture: sudden tendon pain or rupture, especially in the Achilles. - QT prolongation: abnormal heart rhythm detectable on ECG. - Severe allergic reaction: swelling, hives, or breathing difficulty. - Peripheral neuropathy: tingling or numbness in extremities. - Hepatotoxicity: elevated liver enzymes or jaundice. - Clostridioides difficile infection: severe diarrhea after antibiotic use.

What precautions apply to Ofloxacin?

Before prescribing Ofloxacine Biogaren, clinicians should evaluate patient history and potential risk factors. - Renal impairment: adjust dose or monitor renal function. - Hepatic dysfunction: use with caution in liver disease. - Pregnancy: avoid unless clearly needed, discuss risks. - Elderly patients: monitor for tendon injury and CNS effects. - Concomitant QT‑prolonging drugs: assess cardiac risk. - Store at below 25°C: keep in original packaging, protect from moisture and direct sunlight.

What does Ofloxacin interact with?

Ofloxacine Biogaren can interact with several medicines, altering efficacy or safety.

Major Interactions (Avoid): - Antacids containing aluminium or magnesium: reduce absorption of ofloxacin. - Warfarin: may increase anticoagulant effect and bleeding risk. - Non‑steroidal anti‑inflammatory drugs (NSAIDs): heightened risk of CNS stimulation.

Moderate Interactions (Monitor Closely): - Corticosteroids: increased chance of tendon rupture. - Diabetic agents: possible alteration of blood glucose control. - Theophylline: may raise plasma levels and cause toxicity.

Frequently asked questions

What is Ofloxacine Biogaren used for?+
Ofloxacine Biogaren contains ofloxacin, a fluoroquinolone antibiotic used to treat a range of bacterial infections such as urinary tract infections, respiratory tract infections, and skin or soft‑tissue infections when prescribed by a qualified healthcare professional.
How does ofloxacin work?+
Ofloxacin works by inhibiting bacterial DNA gyrase and topoisomerase IV, enzymes that are essential for DNA replication and transcription. This inhibition stops bacterial cells from multiplying, leading to bacterial death and infection resolution.
What is the usual dose of Ofloxacine Biogaren?+
The dosage of Ofloxacine Biogaren is determined by the prescribing clinician based on the type and severity of infection, patient age, weight, kidney function and other clinical factors. Patients should follow the prescriber’s instructions exactly.
Is Ofloxacine Biogaren safe during pregnancy or breastfeeding?+
Ofloxacin is classified as pregnancy category C in many regions, meaning it should only be used if the potential benefit justifies the potential risk to the fetus. It is excreted in breast milk, so breastfeeding mothers should discuss alternatives with their healthcare provider.
How do I order Ofloxacine Biogaren from GNH USA?+
To order, submit an enquiry on the product page at gnh-usa.com specifying the required quantity. GNH USA supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.
How does Ofloxacine Biogaren compare with other fluoroquinolones?+
Ofloxacine Biogaren (ofloxacin) shares the same class mechanism as other fluoroquinolones like ciprofloxacin and levofloxacin but differs in its spectrum of activity, dosing frequency and pharmacokinetic profile. Choice of agent depends on the infection site, bacterial susceptibility and patient‑specific factors.
What are the storage requirements for Ofloxacine Biogaren?+
Store tablets below 25 °C in their original container, protecting them from moisture, heat and direct sunlight. Do not use the product if the packaging is damaged or if the tablets appear discoloured.
How is Ofloxacine Biogaren administered?+
Ofloxacine Biogaren is supplied as oral tablets that should be swallowed whole with a glass of water. It may be taken with or without food, but patients should avoid concurrent intake of antacids containing aluminium or magnesium as they can reduce absorption.
What are the most serious risks associated with Ofloxacine Biogaren?+
Serious risks include tendon rupture, especially of the Achilles tendon, QT‑interval prolongation leading to cardiac arrhythmias, severe allergic reactions, peripheral neuropathy and Clostridioides difficile‑associated colitis. Patients should seek immediate medical attention if they experience related symptoms.
Who should not use Ofloxacine Biogaren?+
Patients with a known hypersensitivity to ofloxacin or other fluoroquinolones, those with a history of tendon disorders related to fluoroquinolone use, and individuals taking medications that significantly prolong the QT interval should avoid Ofloxacine Biogaren unless no alternatives exist.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Ofloxacin
Route
Auricular Use
Manufacturer
Biogaran
Origin
EU

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