Ofloxacine 200 Pch

Ofloxacin, the active ingredient in Ofloxacine 200 Pch, is a fluoroquinolone presented as oral tablets for systemic use. It treats a range of bacterial infections in adults and children when prescribed by a qualified health professional.

GNH USA supplies Ofloxacine 200 Pch as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Ofloxacin is a broad‑spectrum fluoroquinolone antibiotic used to treat infections caused by susceptible bacteria. - Uncomplicated urinary tract infection: eradicates the causative uropathogens and resolves symptoms. - Acute bacterial sinusitis: reduces bacterial load and improves sinus drainage. - Skin and soft‑tissue infections: eliminates common Gram‑negative and Gram‑positive organisms. - Community‑acquired pneumonia: targets typical respiratory pathogens. - Gonorrhea (single‑dose therapy): provides rapid bacterial clearance.

Adverse reactions may occur with Ofloxacin use.

Common Side Effects: - Nausea: mild to moderate gastrointestinal upset. - Diarrhea: loose stools, occasionally watery. - Headache: transient cranial discomfort. - Dizziness: occasional vertiginous sensation. - Photosensitivity: increased skin sensitivity to sunlight. - Rash: mild erythematous skin eruptions.

Serious or Rare Side Effects: - Tendon rupture: sudden pain and loss of function, especially in the Achilles. - QT interval prolongation: risk of cardiac arrhythmias. - Central nervous system effects: seizures, confusion, or hallucinations. - Severe allergic reactions: anaphylaxis, angioedema, or Stevens‑Johnson syndrome. - Hepatotoxicity: elevated liver enzymes or jaundice. - Peripheral neuropathy: tingling or numbness in extremities.

Before prescribing Ofloxacin, consider patient-specific factors and safety measures. - Renal impairment: adjust dose or monitor renal function. - History of tendon disorders: avoid use in patients with prior tendon injury. - Cardiac risk: caution in patients with known QT prolongation. - Pregnancy and lactation: use only if clearly needed, after risk‑benefit assessment. - Concomitant medications: review for potential interactions that may affect cardiac rhythm. - Store at ambient temperature: keep below 25 °C, in the original container, protected from moisture and direct sunlight.

Ofloxacin may interact with other medicines, requiring monitoring or avoidance.

Major Interactions (Avoid): - Antacids containing aluminum or magnesium: reduce Ofloxacin absorption. - Non‑steroidal anti‑inflammatory drugs (NSAIDs): increase risk of CNS stimulation. - Warfarin: may enhance anticoagulant effect, requiring INR monitoring.

Moderate Interactions (Monitor Closely): - Corticosteroids: heightened risk of tendon rupture. - Cyclosporine: may increase serum levels of Ofloxacin. - Theophylline: potential for increased plasma concentrations and toxicity.