Ofloxacin Unimed Pharma

Ofloxacin, the active ingredient in Ofloxacin Unimed Pharma, is a fluoroquinolone antibiotic presented as a tablet for oral use. It treats a range of bacterial infections in adults and children as prescribed by a healthcare professional, including urinary tract, respiratory, and skin infections caused by susceptible organisms.

GNH USA supplies Ofloxacin Unimed Pharma as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides regulatory‑compliant documentation for global distribution.

Ofloxacin is a fluoroquinolone antibiotic used to treat bacterial infections affecting various organ systems.

- Urinary tract infection: eradicates susceptible Gram‑negative and Gram‑positive pathogens, relieving symptoms and preventing complications. - Acute bacterial sinusitis: reduces bacterial load and improves sinus drainage in adults. - Skin and soft‑tissue infection: clears susceptible Staphylococcus and Streptococcus species, promoting wound healing. - Community‑acquired pneumonia: targets common respiratory pathogens, aiding recovery.

Like other fluoroquinolones, Ofloxacin may cause a range of adverse reactions, varying from mild to serious.

Common Side Effects: - Nausea: mild gastrointestinal upset. - Diarrhea: loose stools, often self‑limiting. - Headache: transient cranial discomfort. - Dizziness: occasional vertigo or light‑headedness. - Rash: mild skin erythema or itching.

Serious or Rare Side Effects: - Tendon rupture: especially Achilles, requiring immediate medical attention. - QT interval prolongation: may predispose to cardiac arrhythmias. - Severe allergic reaction: anaphylaxis or angioedema. - Clostridioides difficile colitis: severe diarrhea due to gut flora disruption.

Appropriate use of Ofloxacin requires careful assessment of patient risk factors and clinical conditions. - Hypersensitivity: avoid in patients with known allergy to fluoroquinolones or related compounds. - Tendon disorders: discontinue if tendon pain, swelling, or inflammation occurs. - Cardiac risk: caution in patients with known QT prolongation or electrolyte imbalance. - Pregnancy and lactation: use only if clearly needed, as safety data are limited. - Renal/hepatic impairment: dose adjustment may be required; monitor function. - Pediatric use: reserve for specific indications and weight‑based dosing under supervision. - Store at ambient temperature: keep below 25 °C, retain in original packaging, protect from moisture.

Ofloxacin can interact with several medicines, altering its efficacy or increasing toxicity.

Major Interactions (Avoid): - Antacids containing aluminum or magnesium: chelate Ofloxacin, reducing absorption. - Sucralfate: binds the drug and markedly decreases bioavailability. - Warfarin: may enhance anticoagulant effect, increasing bleeding risk. - Corticosteroids: combined use raises risk of tendon rupture. - Theophylline: Ofloxacin can increase plasma levels, leading to toxicity.

Moderate Interactions (Monitor Closely): - Non‑steroidal anti‑inflammatory drugs (NSAIDs): may increase risk of CNS stimulation. - Diabetes medications (e.g., insulin, sulfonylureas): Ofloxacin may affect glucose control. - Cyclosporine: potential for increased serum concentrations. - Oral contraceptives: may reduce effectiveness; advise additional contraception.