Europe — EMA
Ofloxacin Teva Uk
GNH USA supplies Ofloxacin Teva Uk (Ofloxacin), a fluoroquinolone antibiotic for urinary, respiratory and skin bacterial infections.
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What is Ofloxacin?
Ofloxacin, the active ingredient in Ofloxacin Teva Uk, is a fluoroquinolone antibiotic presented as a tablet for oral use. It treats a range of bacterial infections in adults and children when prescribed by a qualified healthcare professional.
GNH USA supplies Ofloxacin Teva Uk as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.
What is Ofloxacin used for?
Ofloxacin is a broad‑spectrum fluoroquinolone used to treat bacterial infections in several organ systems. - Urinary Tract Infections: eradicates susceptible Gram‑negative and Gram‑positive uropathogens, relieving symptoms and preventing complications. - Respiratory Tract Infections: targets pathogens causing acute exacerbations of chronic bronchitis and community‑acquired pneumonia. - Skin and Soft Tissue Infections: eliminates causative bacteria in cellulitis, abscesses and wound infections. - Gonorrhea: provides effective therapy against Neisseria gonorrhoeae strains susceptible to fluoroquinolones.
What are the side effects of Ofloxacin?
Adverse reactions to ofloxacin can vary in frequency and severity.
Common Side Effects: - Nausea: mild to moderate stomach upset. - Diarrhea: loose stools, occasionally watery. - Headache: transient cranial discomfort. - Dizziness: sensation of light‑headedness. - Abdominal pain: cramping or discomfort. - Rash: mild skin erythema.
Serious or Rare Side Effects: - Tendon rupture: sudden tendon pain or rupture, especially Achilles. - QT interval prolongation: risk of cardiac arrhythmias. - Severe allergic reactions: anaphylaxis, angioedema. - Clostridioides difficile infection: severe colitis. - Peripheral neuropathy: numbness or tingling. - Hepatic dysfunction: elevated liver enzymes or jaundice.
What precautions apply to Ofloxacin?
Before initiating therapy, clinicians should consider several safety aspects. - Renal function assessment: adjust dose in impaired clearance. - Tendon disorder avoidance: do not use in patients with known tendon disease. - Pregnancy caution: avoid unless benefits outweigh risks. - QT monitoring: ECG recommended for patients with cardiac risk factors. - Concomitant medication review: evaluate for interactions that may increase toxicity. - Store at ambient temperature: keep in original packaging, protect from moisture and direct sunlight.
What does Ofloxacin interact with?
Ofloxacin may interact with other medicines, altering efficacy or safety.
Major Interactions (Avoid): - Antacids containing aluminum or magnesium: reduce ofloxacin absorption. - NSAIDs: increase risk of central nervous system adverse effects. - Warfarin: potentiate anticoagulant effect, raising bleeding risk. - Theophylline: elevate plasma levels, risking toxicity. - Cyclosporine: increase cyclosporine concentrations, enhancing nephrotoxicity.
Moderate Interactions (Monitor Closely): - Oral contraceptives: may reduce hormonal efficacy, consider backup method. - Diabetic agents: heightened risk of hypoglycemia. - Corticosteroids: combined use raises tendon rupture risk. - SSRIs: additive effect on QT prolongation. - Rifampin: induces metabolism, lowering ofloxacin exposure.
Frequently asked questions
What infections is Ofloxacin Teva Uk used to treat?+
How does ofloxacin work against bacteria?+
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