Ofloxacin Stada

Ofloxacin, the active ingredient in Ofloxacin Stada, is a fluoroquinolone antibiotic presented as an oral tablet for systemic use. It treats a range of bacterial infections in adults and children when prescribed by a qualified health professional.

GNH USA supplies Ofloxacin Stada as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Ofloxacin is a broad‑spectrum antibacterial that targets Gram‑negative and Gram‑positive organisms in several infection categories.

- Urinary tract infection: eradicates causative bacteria and resolves symptoms such as dysuria and frequency. - Acute exacerbation of chronic bronchitis: reduces bacterial load and improves breathing difficulty. - Skin and soft‑tissue infection: clears cellulitis or wound infections caused by susceptible organisms. - Uncomplicated gonorrhea: eliminates Neisseria gonorrhoeae and prevents transmission. - Bacterial conjunctivitis: treats eye infection and alleviates redness and discharge.

Common Side Effects: - Nausea: mild to moderate stomach upset. - Diarrhea: loose stools that may be self‑limiting. - Headache: transient cranial discomfort. - Dizziness: occasional light‑headed sensation. - Abdominal pain: cramp‑like discomfort. - Rash: mild skin irritation.

Serious or Rare Side Effects: - Tendon rupture: sudden pain and loss of function, especially in the Achilles tendon. - QT interval prolongation: risk of cardiac arrhythmias. - Severe allergic reaction: anaphylaxis, swelling, or breathing difficulty. - Clostridioides difficile infection: severe colitis with watery diarrhea. - Peripheral neuropathy: tingling or numbness in extremities. - Stevens‑Johnson syndrome: severe skin blistering and mucosal involvement.

Before initiating therapy, consider the following safety measures. - Assess renal function: adjust dosing in patients with impaired clearance. - Avoid in patients with known hypersensitivity to fluoroquinolones. - Use with caution in the elderly: higher incidence of tendon injury. - Monitor for QT prolongation when combined with other QT‑affecting agents. - Avoid concurrent use with antacids containing aluminum or magnesium: may reduce absorption. - Store at room temperature: keep in the original container, protect from moisture and light.

Ofloxacin may interact with several medicines; monitoring is essential.

Major Interactions (Avoid): - Antacids or supplements containing aluminum, magnesium, calcium, or iron: decrease Ofloxacin absorption. - Warfarin: increased anticoagulant effect, risk of bleeding. - Cyclosporine: elevated cyclosporine levels, potential nephrotoxicity. - Theophylline: heightened theophylline toxicity. - Oral hypoglycemic agents: enhanced hypoglycaemic effect.

Moderate Interactions (Monitor Closely): - NSAIDs: increased risk of central nervous system stimulation. - Corticosteroids: additive risk of tendon rupture. - Other QT‑prolonging drugs: monitor cardiac rhythm. - Insulin: potential for additive hypoglycaemia. - Oral contraceptives: reduced efficacy, consider alternative contraception.