Ofloxacin-Pos

Ofloxacin, the active ingredient in Ofloxacin-Pos, is a fluoroquinolone antibiotic presented as a tablet for oral use. It treats a range of bacterial infections in adults and children as prescribed.

GNH USA supplies Ofloxacin-Pos as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Ofloxacin is a broad‑spectrum fluoroquinolone used to manage infections caused by susceptible bacteria. - Urinary tract infection: clears infection by targeting common Gram‑negative uropathogens. - Acute bacterial sinusitis: reduces bacterial load in the sinus mucosa. - Skin and soft‑tissue infection: eradicates susceptible Staphylococcus and Streptococcus species. - Gonorrhea: effective against Neisseria gonorrhoeae strains sensitive to fluoroquinolones. - Chronic bacterial prostatitis: penetrates prostatic tissue to treat persistent infection.

Common Side Effects: - Nausea: mild to moderate stomach upset. - Diarrhea: loose stools, often self‑limiting. - Headache: transient cranial discomfort. - Dizziness: occasional light‑headedness. - Rash: mild skin irritation. - Photosensitivity: increased sun sensitivity.

Serious or Rare Side Effects: - Tendon rupture: especially Achilles tendon, requiring immediate medical attention. - QT interval prolongation: may cause cardiac arrhythmias. - Severe allergic reactions: anaphylaxis, angioedema. - Central nervous system effects: seizures, confusion. - Hepatotoxicity: elevated liver enzymes or jaundice. - Peripheral neuropathy: numbness or tingling in extremities.

Before using Ofloxacin, consider the following precautions: - Tendon disorders: avoid use in patients with recent tendon injury or corticosteroid therapy. - Cardiac risk: monitor QT interval in patients with known arrhythmias. - Renal impairment: adjust dose in severe kidney dysfunction. - Hepatic dysfunction: use cautiously in liver disease. - Pregnancy and lactation: avoid unless clearly needed, discuss risks with a healthcare professional. - Storage: Store below 25°C: keep in the original pack, protect from moisture.

Major Interactions (Avoid): - Antacids containing aluminum or magnesium: reduce absorption of Ofloxacin. - Warfarin: may increase anticoagulant effect, requiring INR monitoring. - Cyclosporine: increased risk of neurotoxicity. - Theophylline: may raise plasma levels, leading to toxicity. - Non‑steroidal anti‑inflammatory drugs (NSAIDs): heightened risk of CNS stimulation.

Moderate Interactions (Monitor Closely): - Oral contraceptives: reduced efficacy, advise backup contraception. - Diabetic agents: may affect blood glucose control. - Corticosteroids: increased risk of tendon rupture. - Probenecid: may increase Ofloxacin plasma concentrations. - Rifampin: may lower Ofloxacin levels, reducing effectiveness.