GNH USA

Europe — EMA

Ofloxacin-Ophtal Kombipackung Dr. Gerhard Mann Chem.-Pharm. Fabrik

GNH USA supplies Ofloxacin-Ophtal Kombipackung (Ofloxacin), a fluoroquinolone antibiotic for conjunctivitis, keratitis and eye infections. Contact for supply.

Ofloxacin

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What is Ofloxacin?

Ofloxacin, the active ingredient in Ofloxacin-Ophtal Kombipackung Dr. Gerhard Mann Chem.-Pharm. Fabrik, is a fluoroquinolone antibiotic presented as an ophthalmic solution for ocular use. It treats bacterial conjunctivitis, bacterial keratitis and other ocular bacterial infections in patients of all ages.

GNH USA supplies Ofloxacin-Ophtal Kombipackung Dr. Gerhard Mann Chem.-Pharm. Fabrik as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The product meets EU quality standards and is distributed under strict regulatory compliance.

What is Ofloxacin used for?

Ofloxacin is a fluoroquinolone antibiotic used to treat bacterial infections of the eye.

- Bacterial conjunctivitis: reduces bacterial load and resolves infection symptoms. - Bacterial keratitis: eliminates pathogenic bacteria and promotes corneal healing. - Other ocular bacterial infections: treats a range of bacterial eye conditions, preventing spread and complications.

What are the side effects of Ofloxacin?

Common ocular reactions may occur during treatment.

Common Side Effects: - Eye irritation or burning sensation. - Redness of the conjunctiva. - Excessive tearing. - Blurred vision. - Foreign body sensation. - Mild itching.

Serious or Rare Side Effects: - Severe allergic reaction (e.g., angioedema, anaphylaxis). - Corneal ulceration or perforation. - Significant vision loss. - Persistent eye pain. - Stevens‑Johnson syndrome or toxic epidermal necrolysis. - Hypersensitivity dermatitis affecting the peri‑ocular area.

What precautions apply to Ofloxacin?

Before using Ofloxacin‑Ophtal, consider the following safety measures.

- Allergy assessment: avoid if known hypersensitivity to fluoroquinolones or any excipient. - Contact lens use: discontinue lenses during therapy to reduce irritation risk. - Systemic absorption: limit duration to minimize potential systemic effects. - Pregnancy and lactation: use only if clearly needed after risk‑benefit evaluation. - Drug interactions: inform prescriber of any concurrent ocular medications. - Store at room temperature: keep in original container, protect from light and moisture.

What does Ofloxacin interact with?

Ofloxacin‑Ophtal may interact with other ophthalmic agents.

Major Interactions (Avoid): - Concurrent use with other fluoroquinolone eye drops: increased toxicity risk. - Systemic fluoroquinolones: potential additive systemic exposure. - Topical corticosteroids: may mask infection signs.

Moderate Interactions (Monitor Closely): - Anticholinergic eye drops: possible reduced efficacy. - Non‑steroidal anti‑inflammatory eye drops: monitor for heightened irritation. - Preservative‑containing contact lens solutions: may exacerbate ocular discomfort.

Frequently asked questions

What is Ofloxacin-Ophtal Kombipackung used for?+
Ofloxacin-Ophtal Kombipackung is indicated for the treatment of bacterial eye infections such as conjunctivitis, keratitis and other ocular bacterial conditions. It works by eliminating the causative bacteria, helping to relieve symptoms and prevent complications. The product is applied directly to the eye as directed by a qualified healthcare professional.
How does Ofloxacin work in the eye?+
Ofloxacin belongs to the fluoroquinolone class and exerts its antibacterial effect by inhibiting the bacterial enzymes DNA gyrase and topoisomerase IV. These enzymes are essential for DNA replication and transcription. By blocking them, Ofloxacin prevents bacterial cell division, leading to bacterial death and resolution of the infection.
What is the usual dose of Ofloxacin‑Ophtal?+
The specific dosing regimen for Ofloxacin‑Ophtal is determined by the prescribing clinician based on the type and severity of the infection, patient age, and response to therapy. Typical regimens involve instilling the prescribed number of drops into the affected eye(s) at defined intervals. Patients should follow the exact instructions provided by their eye care professional.
Is Ofloxacin‑Ophtal safe during pregnancy or breastfeeding?+
Safety data for Ofloxacin‑Ophtal in pregnancy and lactation are limited. It should only be used if the potential benefit justifies any potential risk to the fetus or infant. Healthcare providers will assess the individual situation and may recommend alternative treatments when appropriate. Pregnant or nursing patients should discuss all options with their physician.
How do I order Ofloxacin‑Ophtal Kombipackung from GNH USA?+
To place an order, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA supplies hospitals, pharmacies and procurement teams worldwide. After the enquiry, the sales team will verify trade or institutional credentials, then provide pricing, availability, shipping details (including any required temperature control) and assist with import documentation.
How does Ofloxacin‑Ophtal compare with other ocular antibiotics?+
Ofloxacin‑Ophtal is a fluoroquinolone, offering broad‑spectrum activity against Gram‑negative and Gram‑positive ocular pathogens. Compared with older agents such as chloramphenicol or macrolides, fluoroquinolones generally provide faster bacterial eradication and lower resistance rates. However, selection of therapy should consider local resistance patterns, patient tolerance and specific organism susceptibility.
What are the storage and handling requirements for Ofloxacin‑Ophtal?+
The product should be stored at room temperature, preferably below 25 °C, in its original container. Protect the container from light and moisture to maintain stability. Do not freeze the solution. Keep the vial tightly closed when not in use and discard any remaining product after the recommended period after opening, as indicated on the label.
How is Ofloxacin‑Ophtal administered?+
Ofloxacin‑Ophtal is applied as an eye drop. The patient should wash their hands, tilt the head back, and gently pull down the lower eyelid to create a small pocket. One or more drops are placed into the conjunctival sac as prescribed, avoiding contact with the eye or eyelid. The patient should close the eye gently for a few seconds to allow distribution.
What are the most serious risks associated with Ofloxacin‑Ophtal?+
Serious risks include severe allergic reactions such as anaphylaxis, corneal ulceration or perforation, and rare systemic hypersensitivity syndromes like Stevens‑Johnson syndrome. Vision loss may occur if a serious ocular complication develops. Patients should seek immediate medical attention if they experience intense eye pain, sudden vision changes, swelling, or signs of an allergic reaction.
Who should not use Ofloxacin‑Ophtal?+
Individuals with a known hypersensitivity to Ofloxacin, other fluoroquinolones, or any component of the ophthalmic formulation should avoid using the product. It is also contraindicated in patients who have experienced severe adverse reactions to similar eye medications. Clinicians should assess each patient’s medical history before prescribing.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.
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Product details

Drug
Ofloxacin
Route
Ocular Use
Manufacturer
Dr. Gerhard Mann Chem.-Pharm. Fabrik Gmbh
Origin
EU

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